Scholarlink

<p>Label-free optical detection techniques have established themselves as irreplaceable analytical tools across research and industry. The technological leap achieved by several detection modalities, reaching single-molecule sensitivity, opens new frontiers but also raises challenges in defining future biotechnological applications. This review discusses the fundamental principles of optical single-molecule detection, its methodological limitations, and the opportunities arising from recent technological advancements.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Label-free single-molecule optical detection

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月23日

查看全文
  • Tereza Roesel,
  • Andreas Dahlin,
  • Marek Piliarik,
  • Laurence W. Fitzpatrick,
  • Barbora Špačková

摘要

Label-free optical detection techniques have established themselves as irreplaceable analytical tools across research and industry. The technological leap achieved by several detection modalities, reaching single-molecule sensitivity, opens new frontiers but also raises challenges in defining future biotechnological applications. This review discusses the fundamental principles of optical single-molecule detection, its methodological limitations, and the opportunities arising from recent technological advancements.