Scholarlink

<p>The association of pulse pressure (PP) with the severity and cardiovascular (CV) outcomes in stable coronary artery disease populations with normal ejection fraction are sparse. We enrolled 7,027 patients and follow-up 36.4 months, a total of 289 events occurred. Both systolic blood pressure (SBP) and PP were significantly increased by Gensini Score quartiles. Meanwhile, the percentage of 3-diseased vessels was increasing by PP quartiles (<i>p</i> &lt; 0.001). On univariate analysis, both PP and SBP were associated with CV death, stroke, and combined outcome (<i>p</i> &lt; 0.05, all). However, after adjusting for potential confounders, PP remains significantly associated with stroke (HR 95%CI 1.019[1.005–1.033]) and combined outcome (HR 95%CI 1.014[1.005–1.023]) while SBP was only associated with stroke (HR 95%CI 1.014[1.003–1.026]). On multivariate analysis, the highest PP quartile consistently associated with stroke and combined outcome (<i>p</i> &lt; 0.05, all). This prospective cohort study suggesting that PP may be a pivotal predictor for CV risk.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Pulse pressure associates with severity and worse outcomes in patients with stable coronary artery disease

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月4日

查看全文
  • Yan Zhang,
  • Sha Li,
  • Hui-Wen Zhang,
  • Yuan-Lin Guo,
  • Na-Qiong Wu,
  • Cheng-Gang Zhu,
  • Rui-Xia Xu,
  • Jie Qian,
  • Ke-Fei Dou,
  • Jian-Jun Li

摘要

The association of pulse pressure (PP) with the severity and cardiovascular (CV) outcomes in stable coronary artery disease populations with normal ejection fraction are sparse. We enrolled 7,027 patients and follow-up 36.4 months, a total of 289 events occurred. Both systolic blood pressure (SBP) and PP were significantly increased by Gensini Score quartiles. Meanwhile, the percentage of 3-diseased vessels was increasing by PP quartiles (p < 0.001). On univariate analysis, both PP and SBP were associated with CV death, stroke, and combined outcome (p < 0.05, all). However, after adjusting for potential confounders, PP remains significantly associated with stroke (HR 95%CI 1.019[1.005–1.033]) and combined outcome (HR 95%CI 1.014[1.005–1.023]) while SBP was only associated with stroke (HR 95%CI 1.014[1.003–1.026]). On multivariate analysis, the highest PP quartile consistently associated with stroke and combined outcome (p < 0.05, all). This prospective cohort study suggesting that PP may be a pivotal predictor for CV risk.