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<p>This systematic review compared the efficacies of percutaneous mitral balloon commissurotomy (PMBC), mitral valvuloplasty (MVP), and mitral valve replacement (MVR) in patients with rheumatic mitral valve disease. Data from 15,271 patients across 23 cohort studies and randomized controlled trials were analyzed. Based on the results of the network meta-analysis, MVP demonstrated a lower early mortality rate [odds ratio (OR), 0.71; 95% confidence interval (CI): 0.54–0.92], follow-up mortality rate (OR: 0.84; 95% CI: 0.72-0.99), and complication rate (OR: 0.75; 95% CI: 0.64-0.88) compared to MVR. The follow-up reoperation rate in the MVP group was significantly lower than that in the PMBC group (OR: 0.49; 95% CI: 0.30–0.80). The optimal surgical strategy should be tailored to achieve better prognoses.</p>

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Network meta-analysis to compare the efficacies of three surgical techniques in rheumatic mitral valve disease

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月20日

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  • Chuang Liu,
  • Song-hao Jia,
  • Mao-zhou Wang,
  • Ming-xuan Zhang,
  • Xiao-long Wang,
  • Hong-jia Zhang,
  • Wen-jian Jiang

摘要

This systematic review compared the efficacies of percutaneous mitral balloon commissurotomy (PMBC), mitral valvuloplasty (MVP), and mitral valve replacement (MVR) in patients with rheumatic mitral valve disease. Data from 15,271 patients across 23 cohort studies and randomized controlled trials were analyzed. Based on the results of the network meta-analysis, MVP demonstrated a lower early mortality rate [odds ratio (OR), 0.71; 95% confidence interval (CI): 0.54–0.92], follow-up mortality rate (OR: 0.84; 95% CI: 0.72-0.99), and complication rate (OR: 0.75; 95% CI: 0.64-0.88) compared to MVR. The follow-up reoperation rate in the MVP group was significantly lower than that in the PMBC group (OR: 0.49; 95% CI: 0.30–0.80). The optimal surgical strategy should be tailored to achieve better prognoses.