BOADICEA model: updates to the BRCA2 breast cancer risks for ages 60 years and older

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2024年7月24日

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Lorenzo Ficorella,
Xin Yang,
Douglas F. Easton,
Antonis C. Antoniou

摘要

Breast cancer risks in older BRCA2 pathogenic variant carriers are understudied. Recent studies show a marked decline in the relative risk at older ages. We used data from two large studies to update the breast cancer risks in the BOADICEA model for BRCA2 carriers 60 years and older.