Scholarlink

<p>Agriculture is fundamental to ensuring humanity’s food and fibre security. Synthetic pesticides pose challenges due to resistance, emissions, toxicity, and harm to beneficial organisms. A novel approach involves RNA-based biopesticides, eliciting an RNA interference (RNAi) response via topical application of double-stranded RNA (dsRNA), avoiding genetic modification. However, potential issues surrounding RNAi, including policy controversies and regulatory gaps, may affect public perception and acceptance of topical RNAi, impacting the acquisition of a social licence to operate (SLO). This qualitative systematic literature review examines public perceptions of RNAi-based biopesticides, the associated policy considerations and their implications for developing an SLO. The results show that factors influencing public perceptions and SLO emphasise human and environmental safety and costs, including also off-target impacts, degradability, protection window, resistance, toxicity, and ethical and cultural considerations. Finally, we discuss strategies from social science literature for RNAi-biopesticides to achieve an SLO towards sustainability, enhancing food safety and productivity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A systematic review on public perceptions of RNAi-based biopesticides: Developing Social Licence to Operate

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年3月27日

查看全文
  • Raquel Tardin-Coelho,
  • Stephen Fletcher,
  • Narelle Manzie,
  • Sandya Nishanthi Gunasekara,
  • Pedro Fidelman,
  • Neena Mitter,
  • Peta Ashworth

摘要

Agriculture is fundamental to ensuring humanity’s food and fibre security. Synthetic pesticides pose challenges due to resistance, emissions, toxicity, and harm to beneficial organisms. A novel approach involves RNA-based biopesticides, eliciting an RNA interference (RNAi) response via topical application of double-stranded RNA (dsRNA), avoiding genetic modification. However, potential issues surrounding RNAi, including policy controversies and regulatory gaps, may affect public perception and acceptance of topical RNAi, impacting the acquisition of a social licence to operate (SLO). This qualitative systematic literature review examines public perceptions of RNAi-based biopesticides, the associated policy considerations and their implications for developing an SLO. The results show that factors influencing public perceptions and SLO emphasise human and environmental safety and costs, including also off-target impacts, degradability, protection window, resistance, toxicity, and ethical and cultural considerations. Finally, we discuss strategies from social science literature for RNAi-biopesticides to achieve an SLO towards sustainability, enhancing food safety and productivity.