Scholarlink

<p>Antimicrobial resistance (AMR) is increasingly reported in wildlife, yet evidence from Africa remains fragmented. We conducted a systematic review of AMR in African wildlife, screening 4,802 records and including 61 studies from 21 countries. Phenotypic testing was performed in all studies, primarily using disk diffusion (82%), with genotypic assays in 86.8%. Across 4,669 bacterial isolates from 27 eligible studies, the pooled prevalence of phenotypic resistance was 59% (95% CI: 34–80%), with substantial heterogeneity (I² = 97.4%). Wild birds exhibited the highest pooled prevalence (93%), followed by non-human primates (35%) and herbivores (25%). <i>Escherichia coli</i> (20 studies and 3414 isolates) showed a pooled resistance prevalence of 62%. Pooled multidrug resistance was 23.1% (9 studies and 1128 isolates). Sampling was predominantly opportunistic and concentrated in human-impacted environments, limiting ecological inference. These findings highlight significant AMR occurrence across diverse wildlife taxa and substantial gaps in surveillance, coverage, and methodological consistency.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Prevalence and patterns of antimicrobial resistance among wildlife populations in Africa: a systematic review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月16日

查看全文
  • Jemimmah W. Mwangi,
  • Anne Kimeu,
  • Arshnee Moodley,
  • Peter K. Koskei,
  • Katharina Schaufler,
  • Dishon M. Muloi

摘要

Antimicrobial resistance (AMR) is increasingly reported in wildlife, yet evidence from Africa remains fragmented. We conducted a systematic review of AMR in African wildlife, screening 4,802 records and including 61 studies from 21 countries. Phenotypic testing was performed in all studies, primarily using disk diffusion (82%), with genotypic assays in 86.8%. Across 4,669 bacterial isolates from 27 eligible studies, the pooled prevalence of phenotypic resistance was 59% (95% CI: 34–80%), with substantial heterogeneity (I² = 97.4%). Wild birds exhibited the highest pooled prevalence (93%), followed by non-human primates (35%) and herbivores (25%). Escherichia coli (20 studies and 3414 isolates) showed a pooled resistance prevalence of 62%. Pooled multidrug resistance was 23.1% (9 studies and 1128 isolates). Sampling was predominantly opportunistic and concentrated in human-impacted environments, limiting ecological inference. These findings highlight significant AMR occurrence across diverse wildlife taxa and substantial gaps in surveillance, coverage, and methodological consistency.