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<p>Despite the substantial global health and economic burden of apicomplexan parasites in humans and livestock, treatment options remain limited. Natural products have long played an important role in combating these diseases, offering diverse chemical structures and bioactive compounds. This review summarises past and present natural-product-based therapies for six economically significant apicomplexans and explores the potential of revisiting natural products as a source of next-generation treatments.</p>

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A review of natural products as a source of next-generation drugs against apicomplexan parasites

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年6月6日

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  • Emma Y. Mao,
  • Stephen W. Page,
  • Brad E. Sleebs,
  • Maria R. Gancheva,
  • Danny W. Wilson

摘要

Despite the substantial global health and economic burden of apicomplexan parasites in humans and livestock, treatment options remain limited. Natural products have long played an important role in combating these diseases, offering diverse chemical structures and bioactive compounds. This review summarises past and present natural-product-based therapies for six economically significant apicomplexans and explores the potential of revisiting natural products as a source of next-generation treatments.