Scholarlink

Background <p>Infections and antimicrobial resistance are among the main public health issues in the countries affected by war. This study evaluates war’s impact on wound microbiome and antimicrobial resistance distribution among patients treated in Ukrainian civilian hospitals.</p> Methods <p>The patients with combat wounds were treated in the civilian hospitals located in the Northeast of Ukraine from January to April 2024. The wound samples were examined. The isolated microorganisms were identified with further investigation of antimicrobial resistance profiles.</p> Results <p>Here we show the data obtained from the examination of seventy-three wounded soldiers. Wound infections are associated with severe trauma and the middle&#xa0;age of patients. Bacteria were isolated in 56.16% samples with a predominance of gram-negative bacilli. The most frequent isolates are <i>A. baumannii</i> (36%), <i>E. faecalis</i> (12%), and <i>B. cereus</i> (12%). The frequency of multidrug resistance is 84.6%. Each isolated species has a certain sensitivity profile to antibiotics. The number of multidrug-resistant strains among gram-negative bacteria is higher than among gram-positive ones.</p> Conclusions <p>This study shows the dominance of gram-negative bacilli in military personnel with a higher frequency of multidrug-resistant isolates. These complicate the healing process and promote the spread of multidrug-resistant strains within healthcare settings.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

War impact on antimicrobial resistance and bacteriological profile of wound infections in Ukraine

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月24日

查看全文
  • Viktoriia M. Holubnycha,
  • Olena V. Kholodylo

摘要

Background

Infections and antimicrobial resistance are among the main public health issues in the countries affected by war. This study evaluates war’s impact on wound microbiome and antimicrobial resistance distribution among patients treated in Ukrainian civilian hospitals.

Methods

The patients with combat wounds were treated in the civilian hospitals located in the Northeast of Ukraine from January to April 2024. The wound samples were examined. The isolated microorganisms were identified with further investigation of antimicrobial resistance profiles.

Results

Here we show the data obtained from the examination of seventy-three wounded soldiers. Wound infections are associated with severe trauma and the middle age of patients. Bacteria were isolated in 56.16% samples with a predominance of gram-negative bacilli. The most frequent isolates are A. baumannii (36%), E. faecalis (12%), and B. cereus (12%). The frequency of multidrug resistance is 84.6%. Each isolated species has a certain sensitivity profile to antibiotics. The number of multidrug-resistant strains among gram-negative bacteria is higher than among gram-positive ones.

Conclusions

This study shows the dominance of gram-negative bacilli in military personnel with a higher frequency of multidrug-resistant isolates. These complicate the healing process and promote the spread of multidrug-resistant strains within healthcare settings.