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Healthy dietary patterns are associated with exposure to environmental chemicals in a pregnancy cohort

  • Guoqi Yu,
  • Ruijin Lu,
  • Jiaxi Yang,
  • Mohammad L. Rahman,
  • Ling-Jun Li,
  • Dong D. Wang,
  • Qi Sun,
  • Wei Wei Pang,
  • Claire Guivarch,
  • Anna Birukov,
  • Jagteshwar Grewal,
  • Zhen Chen,
  • Cuilin Zhang

摘要

Healthy dietary patterns, such as the alternate Mediterranean diet and alternate Healthy Eating Index, benefit cardiometabolic health. However, several food components of these dietary patterns are primary sources of environmental chemicals. Here, using data from a racially and ethnically diverse US cohort, we show that healthy dietary pattern scores were positively associated with plasma chemical exposure in pregnancy, particularly for the alternate Mediterranean diet and alternate Healthy Eating Index with polychlorinated biphenyls and per- and poly-fluoroalkyl substances. The associations appeared stronger among Asian and Pacific Islanders. These findings suggest that optimizing the benefits of a healthy diet requires concerted regulatory efforts aimed at lowering environmental chemical exposure.