Scholarlink

<p><i>Candidatus</i> Liberibacter asiaticus (<i>C</i>Las), a pathogenic bacterium causing citrus Huanglongbing, forms a mutualistic relationship with the Asian citrus psyllid, <i>Diaphorina citri</i>. However, the underlying molecular mechanisms remain unclear. We find that <i>C</i>Las enhances the development of testes, ovaries, and mating behavior in <i>D. citri</i>. Transcriptome analysis of ovaries reveals that <i>C</i>Las infection upregulates ATP synthesis genes, increasing ATP levels in <i>D. citri</i>. Silencing the <i>ATPSyn-β</i> gene expression reduces ATP content in the ovary and triglyceride and glycogen content in the fat body, thus decreasing ovarian development, mating, and oviposition. ATPSyn-β localizes to the oocyte cell membrane interacts with vitellogenin (Vg), suggesting that it facilitates Vg entry into ovaries. In conclusion, <i>C</i>Las promotes ovarian development in <i>D. citri</i> by upregulating ATPSyn-β, which supports energy production and nutrient supply. This study provides valuable insights into <i>C</i>Las and may inform novel strategies to control citrus Huanglongbing by reducing <i>D. citri</i> populations.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Pathogen promotes insect ovarian development by inducing a dual role of host ATPSyn-β

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月8日

查看全文
  • Chenyang Yuan,
  • Tianyuan Liu,
  • Jiayao Fan,
  • Ning Wang,
  • Yingzhe Yuan,
  • Tao Peng,
  • Yuxi Zhou,
  • Long Yi,
  • Wei Dou,
  • Jinjun Wang

摘要

Candidatus Liberibacter asiaticus (CLas), a pathogenic bacterium causing citrus Huanglongbing, forms a mutualistic relationship with the Asian citrus psyllid, Diaphorina citri. However, the underlying molecular mechanisms remain unclear. We find that CLas enhances the development of testes, ovaries, and mating behavior in D. citri. Transcriptome analysis of ovaries reveals that CLas infection upregulates ATP synthesis genes, increasing ATP levels in D. citri. Silencing the ATPSyn-β gene expression reduces ATP content in the ovary and triglyceride and glycogen content in the fat body, thus decreasing ovarian development, mating, and oviposition. ATPSyn-β localizes to the oocyte cell membrane interacts with vitellogenin (Vg), suggesting that it facilitates Vg entry into ovaries. In conclusion, CLas promotes ovarian development in D. citri by upregulating ATPSyn-β, which supports energy production and nutrient supply. This study provides valuable insights into CLas and may inform novel strategies to control citrus Huanglongbing by reducing D. citri populations.