<p>Antimicrobial resistance (AMR) represents a major One Health issue, driven by a myriad of potential accelerators that include emerging climate and social challenges. There is little doubt about the need for interventions at critical control points to reduce AMR, but addressing AMR within a single realm of One Health (for example, human, animal or environmental) is not sufficient to reduce it. Building on the past decade of research, this Perspective highlights comprehensive, systemic and integrative strategies that address the effects of anthropogenic activities and the complex relationship between humans and the environment as key targets for intersectoral and global action.</p>

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Towards One Health action for addressing antimicrobial resistance in the age of polycrisis

  • Ishi Keenum,
  • Thomas U. Berendonk,
  • Jonas Bonnedahl,
  • Eddie Cytryn,
  • Christophe Dagot,
  • Antti Karkman,
  • Despo Fatta-Kassinos,
  • April Hayes,
  • Alexander Kirschner,
  • Jan-Ulrich Kreft,
  • Célia M. Manaia,
  • Christophe Merlin,
  • Naziza Rahman,
  • Holly Tipper,
  • Máté Vass,
  • Arthur Zastepa,
  • Israel Adedayo Adeoye,
  • Diana Aga,
  • Daniel Gyamfi Amoako,
  • Stella Christou,
  • Leah Marie Clarke,
  • Elena Sara Crotti,
  • Erica Donner,
  • Stefanie Glaeser,
  • María Rincón Gracia,
  • Jianhua Guo,
  • Paulo Henrique Condeixa de França,
  • Mira Cooper-Beknazarova,
  • Ewa Korzeniewska,
  • Opeyemi U. Lawal,
  • Gonçalo Macedo,
  • M. Moniruzzaman,
  • Donald Morrison,
  • Sarah Jane Payne,
  • Ana Puljko,
  • Svjetlana Dekić Rozman,
  • Carsten Ulrich Schwermer,
  • Ed Topp,
  • Marko Virta

摘要

Antimicrobial resistance (AMR) represents a major One Health issue, driven by a myriad of potential accelerators that include emerging climate and social challenges. There is little doubt about the need for interventions at critical control points to reduce AMR, but addressing AMR within a single realm of One Health (for example, human, animal or environmental) is not sufficient to reduce it. Building on the past decade of research, this Perspective highlights comprehensive, systemic and integrative strategies that address the effects of anthropogenic activities and the complex relationship between humans and the environment as key targets for intersectoral and global action.