Scholarlink

<p>Systematic reviews provide the highest level of evidence but remain resource-intensive. We evaluated the performance of a large language model (LLM; ChatGPT, OpenAI) in a PRISMA-guided review of randomized controlled trials on vaginal vault prolapse surgery. Prompts were carefully designed to minimize errors, and outputs were verified. Each task was completed within minutes. For title/abstract screening, recall was 69.8% and precision 85.7% (κ = 0.77); full-text agreement 94.1–100% (κ = 0.82–1); data extraction accuracy 87.5–99.7%. From 18 RCTs (1668 women), sacrocolpopexy (SC) showed higher anatomic success than sacrospinous fixation (SSF) (OR 1.42, 95% CI 0.71–2.84). Transvaginal mesh improved 3-year objective success compared with SSF (OR 1.84, 95% CI 1.13–2.99) but had higher reoperation rates (5–16% vs 2–4%) than SC. We did not find conclusive evidence that any single technique is superior; most comparisons were underpowered, with wide confidence intervals and substantial heterogeneity. All LLM-derived statistical results were identical to those from conventional R analyses, confirming robustness. Validated LLM workflows can enable more efficient and scalable evidence synthesis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Large language models in systematic review and meta-analysis of surgical treatments for vaginal vault prolapse

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月19日

查看全文
  • Yunjeong Park,
  • Hyun-Soo Zhang,
  • Sang Wook Bai

摘要

Systematic reviews provide the highest level of evidence but remain resource-intensive. We evaluated the performance of a large language model (LLM; ChatGPT, OpenAI) in a PRISMA-guided review of randomized controlled trials on vaginal vault prolapse surgery. Prompts were carefully designed to minimize errors, and outputs were verified. Each task was completed within minutes. For title/abstract screening, recall was 69.8% and precision 85.7% (κ = 0.77); full-text agreement 94.1–100% (κ = 0.82–1); data extraction accuracy 87.5–99.7%. From 18 RCTs (1668 women), sacrocolpopexy (SC) showed higher anatomic success than sacrospinous fixation (SSF) (OR 1.42, 95% CI 0.71–2.84). Transvaginal mesh improved 3-year objective success compared with SSF (OR 1.84, 95% CI 1.13–2.99) but had higher reoperation rates (5–16% vs 2–4%) than SC. We did not find conclusive evidence that any single technique is superior; most comparisons were underpowered, with wide confidence intervals and substantial heterogeneity. All LLM-derived statistical results were identical to those from conventional R analyses, confirming robustness. Validated LLM workflows can enable more efficient and scalable evidence synthesis.