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<p>Mobile health interventions for behavioral change require large-scale studies to ensure their clinical benefits. We conducted a randomized controlled trial of patients with hypertension to assess the myBPmyLife application in promoting physical activity and lower-sodium foods to lower systolic blood pressure (SBP). 602 participants were randomly assigned to either a control group or an intervention group that received the myBPmyLife application. For the primary outcome, change in SBP over 6 months was −5.2 mmHg in the intervention and −5.7 mmHg in the control group (<i>p</i> = 0.76). For secondary outcomes, the intervention group increased their daily step count by 170 steps, while the control group decreased by 319 steps (<i>p</i> = 0.040). Sodium intake decreased by 1145 mg in the intervention and 860 mg in the control group (<i>p</i> = 0.002). The myBPmyLife application did not reduce SBP over 6 months in hypertension patients despite increasing step counts and lowering sodium intake. <b>ClinicalTrials.gov registration</b>: NCT05154929, 12/2021</p>

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Physical activity and diet just-in-time adaptive intervention to reduce blood pressure: a randomized controlled trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月14日

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  • Michael P. Dorsch,
  • Jessica R. Golbus,
  • Rachel Stevens,
  • Brad Trumpower,
  • Tanima Basu,
  • Evan Luff,
  • Kimberly Warden,
  • Michael Giacalone,
  • Sarah Bailey,
  • Gabriella V. Rubick,
  • Sonali Mishra,
  • Predrag Klasnja,
  • Mark W. Newman,
  • Lesli E. Skolarus,
  • Brahmajee K. Nallamothu

摘要

Mobile health interventions for behavioral change require large-scale studies to ensure their clinical benefits. We conducted a randomized controlled trial of patients with hypertension to assess the myBPmyLife application in promoting physical activity and lower-sodium foods to lower systolic blood pressure (SBP). 602 participants were randomly assigned to either a control group or an intervention group that received the myBPmyLife application. For the primary outcome, change in SBP over 6 months was −5.2 mmHg in the intervention and −5.7 mmHg in the control group (p = 0.76). For secondary outcomes, the intervention group increased their daily step count by 170 steps, while the control group decreased by 319 steps (p = 0.040). Sodium intake decreased by 1145 mg in the intervention and 860 mg in the control group (p = 0.002). The myBPmyLife application did not reduce SBP over 6 months in hypertension patients despite increasing step counts and lowering sodium intake. ClinicalTrials.gov registration: NCT05154929, 12/2021