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<p>Mindfulness and relaxation exercises are effective face-to-face interventions for reducing distress in people with cancer. Their effectiveness in mobile health settings has yet to be investigated. This study evaluated the effectiveness of the CanRelax 2 app in reducing distress in people with cancer. German-speaking adults diagnosed with cancer within the last five years with elevated distress levels (Distress Thermometer ≥5) were recruited. Participants were randomized to the CanRelax 2 app or a waitlist control group. The primary endpoint was the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS) after 10 weeks (210 participants). We observed a clinically meaningful larger reduction in PHQ-ADS scores in the intervention group compared to the control group (−3.7, 95%-CI from −5.7 to −1.6; <i>p</i> = 0.0005). Similar effects were found for distress, well-being, and self-regulation. Our results confirm the effectiveness of a mobile health app in reducing distress in people with cancer. Registration: German Clinical Trials Register (DRKS00027546) on 23.02.2022</p>

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Mobile health intervention CanRelax reduces distress in people with cancer in a randomized controlled trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月10日

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  • Jürgen Barth,
  • Sonja Schläpfer,
  • Fabian Schneider,
  • Prabhakaran Santhanam,
  • Tobias Kowatsch,
  • Priska Heinz,
  • Ulrike Held,
  • Manuela Eicher,
  • Claudia M. Witt

摘要

Mindfulness and relaxation exercises are effective face-to-face interventions for reducing distress in people with cancer. Their effectiveness in mobile health settings has yet to be investigated. This study evaluated the effectiveness of the CanRelax 2 app in reducing distress in people with cancer. German-speaking adults diagnosed with cancer within the last five years with elevated distress levels (Distress Thermometer ≥5) were recruited. Participants were randomized to the CanRelax 2 app or a waitlist control group. The primary endpoint was the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS) after 10 weeks (210 participants). We observed a clinically meaningful larger reduction in PHQ-ADS scores in the intervention group compared to the control group (−3.7, 95%-CI from −5.7 to −1.6; p = 0.0005). Similar effects were found for distress, well-being, and self-regulation. Our results confirm the effectiveness of a mobile health app in reducing distress in people with cancer. Registration: German Clinical Trials Register (DRKS00027546) on 23.02.2022