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PatchSorter: a high throughput deep learning digital pathology tool for object labeling

  • Cédric Walker,
  • Tasneem Talawalla,
  • Robert Toth,
  • Akhil Ambekar,
  • Kien Rea,
  • Oswin Chamian,
  • Fan Fan,
  • Sabina Berezowska,
  • Sven Rottenberg,
  • Anant Madabhushi,
  • Marie Maillard,
  • Laura Barisoni,
  • Hugo Mark Horlings,
  • Andrew Janowczyk

摘要

The discovery of patterns associated with diagnosis, prognosis, and therapy response in digital pathology images often requires intractable labeling of large quantities of histological objects. Here we release an open-source labeling tool, PatchSorter, which integrates deep learning with an intuitive web interface. Using >100,000 objects, we demonstrate a >7x improvement in labels per second over unaided labeling, with minimal impact on labeling accuracy, thus enabling high-throughput labeling of large datasets.