<p>Earth’s climate sensitivity quantifies the ultimate change in global mean surface air temperature in response to a doubling of atmospheric CO₂ concentrations. Recent assessments estimate that Earth’s climate sensitivity <i>very likely</i> lies between 2.3 °C and 4.7 °C, with the representation of clouds in climate models accounting for a large portion of its uncertainty. Here, we adjust the climate sensitivity of individual contemporary climate models after using satellite observations to alleviate biases in their representation of mixed-phase clouds. A resulting moderate average climate sensitivity of 3.63 ± 0.98(1<i>σ</i>) °C arises due to opposing responses of clouds. While increasing the proportion of liquid within cold clouds prior to CO₂ doubling increases climate sensitivity via transitions from solid to liquid hydrometeors, a strongly opposing increase in reflective cloud cover decreases climate sensitivity. This emphasizes the need to reconsider the role of mixed-phase cloud cover changes in climate sensitivity assessments.</p>