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<p>Meconium-stained amniotic fluid is a common obstetric condition associated with adverse birth outcomes and fetal compromise, contributing to neonatal morbidity and mortality. However, evidence on its prevalence, associated factors, and birth outcomes in Ethiopia remains limited. To assess the Prevalence, Associated Factors, and Birth Outcomes of Meconium-Stained Amniotic Fluid among Mothers Delivering at Woldia Comprehensive Specialized Hospital, Northern Ethiopia. An institution-based cross-sectional study was conducted at Woldia Comprehensive Specialized Hospital from 1 to 30 November 2025. A total of 358 mothers were selected using a systematic random sampling technique, and 355 were included in the final analysis. Data were collected using a pretested structured questionnaire and medical chart review and captured electronically using KoboToolbox. Data were analyzed using SPSS version 27. Multivariable logistic regression analyses were performed to identify factors associated with meconium-stained amniotic fluid and to assess its association with neonatal birth outcomes. Adjusted odds ratios with 95% confidence intervals were reported, and statistical significance was declared at <i>p</i> &lt; 0.05. The prevalence of meconium-stained amniotic fluid was 17.7% (95% CI: 14.1–21.7). In the multivariable logistic regression analysis, MSAF was significantly associated with maternal chronic medical illness (AOR = 3.86; 95% CI: 1.80–19.19), twin pregnancy (AOR = 2.90; 95% CI: 1.37–20.12), induction of labor (AOR = 2.76; 95% CI: 1.45–8.12), premature rupture of membranes (AOR = 2.60; 95% CI: 2.02–10.34), and pregnancy-induced hypertension (AOR = 3.02; 95% CI: 1.65–9.83). After adjustment for potential confounders, MSAF was significantly associated with low 5-minute Apgar score (AOR = 2.99; 95% CI: 1.74–6.98), birth asphyxia (AOR = 3.24; 95% CI: 1.90–6.67), and the need for neonatal resuscitation (AOR = 2.20; 95% CI: 1.59–5.12). In this study, the prevalence of meconium-stained amniotic fluid was 17.7% (95% CI: 14.1%–21.7%). Maternal chronic illness, twin pregnancy, premature rupture of membranes, pregnancy-induced hypertension, and labor induction were identified as significant factors associated with MSAF. Additionally, MSAF was associated with adverse neonatal outcomes, including low 5-minute Apgar scores, birth asphyxia, and an increased need for neonatal resuscitation. These findings highlight the importance of early recognition of risk factors, continuous intrapartum monitoring, and timely obstetric and neonatal care to improve perinatal outcomes.</p>

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Factors associated with meconium stained amniotic fluid and birth outcomes among mothers at Woldia Comprehensive Specialized Hospital

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月28日

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  • Tadele Emagneneh,
  • Aynalem Yetwale,
  • Abebaw Alamrew,
  • Alemnew Wendimu,
  • Gemeda Kusse,
  • Rahmet Adem,
  • Amanuel Tebebal Nega,
  • Abebe Kassa Geto,
  • Chalie Mulugeta

摘要

Meconium-stained amniotic fluid is a common obstetric condition associated with adverse birth outcomes and fetal compromise, contributing to neonatal morbidity and mortality. However, evidence on its prevalence, associated factors, and birth outcomes in Ethiopia remains limited. To assess the Prevalence, Associated Factors, and Birth Outcomes of Meconium-Stained Amniotic Fluid among Mothers Delivering at Woldia Comprehensive Specialized Hospital, Northern Ethiopia. An institution-based cross-sectional study was conducted at Woldia Comprehensive Specialized Hospital from 1 to 30 November 2025. A total of 358 mothers were selected using a systematic random sampling technique, and 355 were included in the final analysis. Data were collected using a pretested structured questionnaire and medical chart review and captured electronically using KoboToolbox. Data were analyzed using SPSS version 27. Multivariable logistic regression analyses were performed to identify factors associated with meconium-stained amniotic fluid and to assess its association with neonatal birth outcomes. Adjusted odds ratios with 95% confidence intervals were reported, and statistical significance was declared at p < 0.05. The prevalence of meconium-stained amniotic fluid was 17.7% (95% CI: 14.1–21.7). In the multivariable logistic regression analysis, MSAF was significantly associated with maternal chronic medical illness (AOR = 3.86; 95% CI: 1.80–19.19), twin pregnancy (AOR = 2.90; 95% CI: 1.37–20.12), induction of labor (AOR = 2.76; 95% CI: 1.45–8.12), premature rupture of membranes (AOR = 2.60; 95% CI: 2.02–10.34), and pregnancy-induced hypertension (AOR = 3.02; 95% CI: 1.65–9.83). After adjustment for potential confounders, MSAF was significantly associated with low 5-minute Apgar score (AOR = 2.99; 95% CI: 1.74–6.98), birth asphyxia (AOR = 3.24; 95% CI: 1.90–6.67), and the need for neonatal resuscitation (AOR = 2.20; 95% CI: 1.59–5.12). In this study, the prevalence of meconium-stained amniotic fluid was 17.7% (95% CI: 14.1%–21.7%). Maternal chronic illness, twin pregnancy, premature rupture of membranes, pregnancy-induced hypertension, and labor induction were identified as significant factors associated with MSAF. Additionally, MSAF was associated with adverse neonatal outcomes, including low 5-minute Apgar scores, birth asphyxia, and an increased need for neonatal resuscitation. These findings highlight the importance of early recognition of risk factors, continuous intrapartum monitoring, and timely obstetric and neonatal care to improve perinatal outcomes.