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<p>Artificial intelligence (AI) and high-performance computing (HPC) are transforming scientific capabilities and the way science is conducted. Yet their combined impact on scientific discovery remains poorly understood, as do inequalities in access to these capabilities across countries and institutions. Drawing on metadata from more than five million scientific publications (2000–2024) across 27 fields, we examine how the convergence of AI and HPC correlates with scientific breakthroughs. Our results show that this computational synergy is most pronounced at the scientific frontier: research combining AI and HPC is more likely to introduce novel ideas and achieve top-cited status than either conventional work or research using AI or HPC in isolation. We also document growing disparities in access to supercomputing resources and AI expertise, which are increasingly concentrated in a small number of regions (dominated by the United States and China, though the EU27 aggregate maintains high competitiveness in combined AI+HPC output). The future of discovery will depend not only on advances in algorithms and computing power, but also on enacting policies that democratise these capabilities across the global scientific ecosystem.</p>

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Scientific discovery in the age of AI and supercomputing

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月25日

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  • Stefano Bianchini,
  • Aldo Geuna,
  • Fazliddin Shermatov

摘要

Artificial intelligence (AI) and high-performance computing (HPC) are transforming scientific capabilities and the way science is conducted. Yet their combined impact on scientific discovery remains poorly understood, as do inequalities in access to these capabilities across countries and institutions. Drawing on metadata from more than five million scientific publications (2000–2024) across 27 fields, we examine how the convergence of AI and HPC correlates with scientific breakthroughs. Our results show that this computational synergy is most pronounced at the scientific frontier: research combining AI and HPC is more likely to introduce novel ideas and achieve top-cited status than either conventional work or research using AI or HPC in isolation. We also document growing disparities in access to supercomputing resources and AI expertise, which are increasingly concentrated in a small number of regions (dominated by the United States and China, though the EU27 aggregate maintains high competitiveness in combined AI+HPC output). The future of discovery will depend not only on advances in algorithms and computing power, but also on enacting policies that democratise these capabilities across the global scientific ecosystem.