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<p>Tuberculosis hurts the health-related quality of life (HRQOL) and psychological well-being of patients. There is limited evidences regarding the assessment of HRQOL among patients with pulmonary tuberculosis in the study area. Therefore, this study aimed to examine the health-related quality of life and its determinants among patients with pulmonary tuberculosis in Tigray, northern Ethiopia. This was an institutional-based cross-sectional study design conducted among 360 patients. Participants were selected using a systematic random sampling technique. Data were collected using a Medical Outcome Study Short Form (MOS SF-36) questionnaire. A multivariate linear regression model was utilized, and 95% confidence intervals with p-values ≤ 0.05 were considered for statistical significance. The HRQOL mean score among participants was 47.6(SD ± 18.7). The score of Physical Component Summary (PCS) was 50.1(SD ± 22.2), while the Mental Component Summary (MCS) was 45.2(SD ± 16.5). Multivariable linear regression analysis indicated that being male (B = 5.89, <i>p =</i> 0.001), no formal educational(B = 5.51, <i>p =</i> 0.004), intensive phase(B = 5.59, <i>p =</i> 0.010), and treatment support (B=-5.19, <i>p</i> = 0.023) were predictors of PCS score. Similarly, no formal educational(B = 5.15, <i>p</i> = 0.001), intensive phase(B = 4.77, <i>p</i> = 0.001), and treatment support (B=-2.93, <i>p</i> = 0.045) were predictors of MCS score. Our findings indicated that both PCS and MCS components of HRQOL among patients with pulmonary tuberculosis were affected, with the mental health component being notably impacted. No formal educational status, treatment phase, and treatment support were associated factors with PCS and MCS scores.</p>

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Assessment of health-related quality of life and determinants among pulmonary tuberculosis patients, Northern Ethiopia: a cross-sectional study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月10日

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  • Gebrhud Berihu Haile,
  • Jinjin Gu,
  • Panpan Wang,
  • Shujing Suo,
  • Shitong Guo,
  • Ya Li,
  • Peng Wang

摘要

Tuberculosis hurts the health-related quality of life (HRQOL) and psychological well-being of patients. There is limited evidences regarding the assessment of HRQOL among patients with pulmonary tuberculosis in the study area. Therefore, this study aimed to examine the health-related quality of life and its determinants among patients with pulmonary tuberculosis in Tigray, northern Ethiopia. This was an institutional-based cross-sectional study design conducted among 360 patients. Participants were selected using a systematic random sampling technique. Data were collected using a Medical Outcome Study Short Form (MOS SF-36) questionnaire. A multivariate linear regression model was utilized, and 95% confidence intervals with p-values ≤ 0.05 were considered for statistical significance. The HRQOL mean score among participants was 47.6(SD ± 18.7). The score of Physical Component Summary (PCS) was 50.1(SD ± 22.2), while the Mental Component Summary (MCS) was 45.2(SD ± 16.5). Multivariable linear regression analysis indicated that being male (B = 5.89, p = 0.001), no formal educational(B = 5.51, p = 0.004), intensive phase(B = 5.59, p = 0.010), and treatment support (B=-5.19, p = 0.023) were predictors of PCS score. Similarly, no formal educational(B = 5.15, p = 0.001), intensive phase(B = 4.77, p = 0.001), and treatment support (B=-2.93, p = 0.045) were predictors of MCS score. Our findings indicated that both PCS and MCS components of HRQOL among patients with pulmonary tuberculosis were affected, with the mental health component being notably impacted. No formal educational status, treatment phase, and treatment support were associated factors with PCS and MCS scores.