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<p>Incorrect suctioning can have several adverse effects. This study aimed to determine the effectiveness of minimally invasive pre-measured endotracheal tube suctioning on physiological indicators in mechanically ventilated infants. In this crossover clinical trial study, 40 term infants admitted tithe NICU of Amirkola Children’s Hospital were randomly allocated to two groups with 20 infants in each group. In group A, infants first received pre-measured suction for 12&#xa0;h, then routine suction for the next 12&#xa0;h, and in group B, infants first received routine suction and then underwent pre-measured suction. Physiological indicators related to one minute before, during, one, two, five and ten minutes after suction and the time to return to baseline were recorded in the two groups. The mean differences in blood oxygen saturation (%) between the two suction methods at various time points were as follows: During suction, −1.95% (95% CI −2.99 to −0.90); 1&#xa0;min post-suction, −2.25% (95% CI: −3.29 to − 1.20); 2&#xa0;min, −2.42% (95% CI −3.43 to − 1.41); 5&#xa0;min, −2.15% (95% CI −3.23 to −1.06); and 10&#xa0;min, −2.35% (95% CI −3.18 to − 1.52) (<i>P</i> &lt; 0.001). The time required for physiological parameters to return to baseline before suctioning was shorter with the pre-measured method compared with the routine method (<i>P</i> &lt; 0.05). The fluctuations of physiological indicators, especially blood oxygen saturation, in the pre-measured suction method were lower than the routine method.</p>

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Effectiveness of minimally invasive pre-measured endotracheal tube suction on physiological indicators in mechanically ventilated infants: a clinical trial study

  • 期刊论文

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  • 发表日期：

    2026年7月7日

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  • Sedigheh Khanzad,
  • Samira Pournajaf,
  • Afsaneh Arzani,
  • Hossein-Ali Nikbakht,
  • Seyedeh Roghayeh Jafarian-Amiri,
  • Ali Zabihi

摘要

Incorrect suctioning can have several adverse effects. This study aimed to determine the effectiveness of minimally invasive pre-measured endotracheal tube suctioning on physiological indicators in mechanically ventilated infants. In this crossover clinical trial study, 40 term infants admitted tithe NICU of Amirkola Children’s Hospital were randomly allocated to two groups with 20 infants in each group. In group A, infants first received pre-measured suction for 12 h, then routine suction for the next 12 h, and in group B, infants first received routine suction and then underwent pre-measured suction. Physiological indicators related to one minute before, during, one, two, five and ten minutes after suction and the time to return to baseline were recorded in the two groups. The mean differences in blood oxygen saturation (%) between the two suction methods at various time points were as follows: During suction, −1.95% (95% CI −2.99 to −0.90); 1 min post-suction, −2.25% (95% CI: −3.29 to − 1.20); 2 min, −2.42% (95% CI −3.43 to − 1.41); 5 min, −2.15% (95% CI −3.23 to −1.06); and 10 min, −2.35% (95% CI −3.18 to − 1.52) (P < 0.001). The time required for physiological parameters to return to baseline before suctioning was shorter with the pre-measured method compared with the routine method (P < 0.05). The fluctuations of physiological indicators, especially blood oxygen saturation, in the pre-measured suction method were lower than the routine method.