Satisfaction with facial appearance after maxillomandibular advancement in East Asian Patients - a systematic review and meta-analysis
摘要
Maxillomandibular advancement (MMA) is highly effective for obstructive sleep apnea (OSA) but may compromise facial aesthetics in East Asian patients due to bimaxillary protrusion. Two modifications address this: maxillary counterclockwise rotation with no segmental surgery (MaxCCWR) and maxillary anterior segmental osteotomy (MaxASO). A PRISMA 2020-compliant systematic review and meta-analysis was conducted (PROSPERO: CRD420261296073). PubMed, Embase, Web of Science, and Cochrane were searched to 5th February 2026. Studies reporting MMA for OSA in East or Southeast Asian adults with aesthetic outcomes were eligible. Random-effects proportion meta-analysis pooled the proportion of satisfied patients. Fourteen studies (n=167) were included. Most patients were skeletal Class II (mean age 34.49 ± 9.92 years; 73.7% male). The pooled proportion satisfied was 0.83 (95% CI [0.76; 0.87]; I2=0%), with no significant difference between MaxCCWR and MaxASO (0.82 vs 0.84; p=0.75). MaxCCWR proclines while MaxASO retroclines the maxillary incisors, reflecting divergent strategies toward the same aesthetic goal. AHI reduced from 52.17 ± 20.13 to 9.65 ± 7.32 events/h (pooled mean change −44.0 events/h, 95% CI [−51.8, −36.3]); the between-group difference was not significant (p=0.99). Improvements in lowest oxygen saturation and Epworth Sleepiness Scale scores were comparable between modifications (p=0.35 and p=0.30, respectively). Both MaxCCWR and MaxASO mitigate aesthetic concerns while achieving substantial OSA improvement in East Asian patients.