Scholarlink

<p>Polar marine invertebrate giants are proposed to have emerged from the greater availability of environmental oxygen, overcoming the viscosity of cold water and avoiding oxygen poisoning. However, molecular evidence on their metabolic adaptations is lacking to date. Consequently, we characterised the metabolome profiles of a number of marine Antarctic giants and their regular-size relatives exposed acutely in the laboratory either under mean seasonal conditions or elevated temperature. Giants from very distinct taxa share the differential utilisation of metabolic pathways involved in energy production, suggesting an adaptive convergence of metabolic reprogramming to meet the challenge of possessing larger bodies and facing harsh polar conditions. Further, we show that giants are not just larger regular-size species, as indicated by a breakpoint in the allometric relationship for metabolomics scores. Finally, giants do not appear to be more sensitive to ocean warming when compared to their regular-size relatives, all species tested showing no short-term metabolomics reprogramming under elevated temperatures.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Adaptive metabolic reprogramming conserves energy status in Antarctic giants

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月17日

查看全文
  • Piero Calosi,
  • Lauric Feugere,
  • Fanny Vermandele,
  • Paulina Bruning,
  • Mathieu Millour,
  • Bertrand Genard,
  • Ignacio Garrido,
  • Luis Miguel Pardo

摘要

Polar marine invertebrate giants are proposed to have emerged from the greater availability of environmental oxygen, overcoming the viscosity of cold water and avoiding oxygen poisoning. However, molecular evidence on their metabolic adaptations is lacking to date. Consequently, we characterised the metabolome profiles of a number of marine Antarctic giants and their regular-size relatives exposed acutely in the laboratory either under mean seasonal conditions or elevated temperature. Giants from very distinct taxa share the differential utilisation of metabolic pathways involved in energy production, suggesting an adaptive convergence of metabolic reprogramming to meet the challenge of possessing larger bodies and facing harsh polar conditions. Further, we show that giants are not just larger regular-size species, as indicated by a breakpoint in the allometric relationship for metabolomics scores. Finally, giants do not appear to be more sensitive to ocean warming when compared to their regular-size relatives, all species tested showing no short-term metabolomics reprogramming under elevated temperatures.