Scholarlink

<p>Pemphigus is a rare, chronic, recurrent, and life-threatening autoimmune blistering skin disease that imposes a substantial burden on patients, their families, and society. However, information regarding the familial burden associated with pemphigus remains limited. This study aimed to assess the family burden experienced by caregivers of pemphigus patients and to identify relevant contributing factors. From December 2020 to December 2022, a total of 163 patient-caregiver dyads were enrolled in the study. Caregivers completed the Family Burden Scale of Diseases. Univariate logistic regression and multivariate logistic regression were utilized to explore factors influencing family burden. Among the 163 caregivers included in the study, the median Family Burden Scale score was 26 (IQR: 18–36), with 94 caregivers (57.7%) reporting moderate to severe family burden. In the multivariate logistic regression analysis, several factors were found to be significantly associated with family burden among pemphigus patients: medical insurance (adjusted odds ratio [aOR] 3.122, 95% confidence interval [CI] 1.749–5.574), disease type (aOR 0.201, 95% CI 0.050–0.803), Pemphigus Disease Area Index score (aOR 1.116, 95% CI 1.054–1.181), degree of disease severity (aOR 2.089, 95% CI 1.029–4.238), presence of comorbidities (aOR 3.712, 95% CI 1.378–9.999), and caregiver gender (aOR 3.244, 95% CI 1.258–8.362). This study confirms that pemphigus imposes a significant burden on families, highlighting the necessity for healthcare providers to develop and implement family-centered support programs aimed at alleviating this burden.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Family burden of disease in pemphigus: a cross-sectional survey

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月12日

查看全文
  • Hui Gou,
  • Qin Zou,
  • Hongmei Xiang,
  • Zhiqiu Lin,
  • Yibo Luo,
  • Yu Chen,
  • Xingli Zhou,
  • Wei Li,
  • Jihui Chen

摘要

Pemphigus is a rare, chronic, recurrent, and life-threatening autoimmune blistering skin disease that imposes a substantial burden on patients, their families, and society. However, information regarding the familial burden associated with pemphigus remains limited. This study aimed to assess the family burden experienced by caregivers of pemphigus patients and to identify relevant contributing factors. From December 2020 to December 2022, a total of 163 patient-caregiver dyads were enrolled in the study. Caregivers completed the Family Burden Scale of Diseases. Univariate logistic regression and multivariate logistic regression were utilized to explore factors influencing family burden. Among the 163 caregivers included in the study, the median Family Burden Scale score was 26 (IQR: 18–36), with 94 caregivers (57.7%) reporting moderate to severe family burden. In the multivariate logistic regression analysis, several factors were found to be significantly associated with family burden among pemphigus patients: medical insurance (adjusted odds ratio [aOR] 3.122, 95% confidence interval [CI] 1.749–5.574), disease type (aOR 0.201, 95% CI 0.050–0.803), Pemphigus Disease Area Index score (aOR 1.116, 95% CI 1.054–1.181), degree of disease severity (aOR 2.089, 95% CI 1.029–4.238), presence of comorbidities (aOR 3.712, 95% CI 1.378–9.999), and caregiver gender (aOR 3.244, 95% CI 1.258–8.362). This study confirms that pemphigus imposes a significant burden on families, highlighting the necessity for healthcare providers to develop and implement family-centered support programs aimed at alleviating this burden.