<p>This study demonstrates a one-step hydrothermal synthesis of bright yellow phosphorus-doped carbon quantum dots (P-CQDs) using <i>Caesalpinia sappan L.</i> as carbon source. Comprehensive characterization through TEM, XPS, UV-Vis and FTIRspectroscopy confirmed the successful formation of P-CQDs. The obtained P-CQDs exhibited exceptional selectivity and was capable of detecting ciprofloxacin across a wide linear range of 0.01–0.1 µM, with a LOD determined to be 2.06 nM. Antimicrobial assays revealed MIC values of 7.14&#xa0;µg/mL and 8.33&#xa0;µg/mL against <i>S. aureus</i> and <i>E. coli</i>, respectively. Practical application studies confirmed their efficacy for rapid CIP detection in milk samples, establishing a novel sensing platform for food safety monitoring. This work provides valuable insights into the multifunctional applications of carbon dots in food chemistry and biomedical fields.</p>

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Preparation of carbon quantum dot fluorescent probe from Caesalpinia sappan L. for the detection of ciprofloxacin and antibacterial applications

  • Shuchen Pei,
  • Kangli Yan,
  • Shaoyu Cai,
  • Yinjun Hou,
  • Kang Luo,
  • Pu Xiang,
  • Yang Peng

摘要

This study demonstrates a one-step hydrothermal synthesis of bright yellow phosphorus-doped carbon quantum dots (P-CQDs) using Caesalpinia sappan L. as carbon source. Comprehensive characterization through TEM, XPS, UV-Vis and FTIRspectroscopy confirmed the successful formation of P-CQDs. The obtained P-CQDs exhibited exceptional selectivity and was capable of detecting ciprofloxacin across a wide linear range of 0.01–0.1 µM, with a LOD determined to be 2.06 nM. Antimicrobial assays revealed MIC values of 7.14 µg/mL and 8.33 µg/mL against S. aureus and E. coli, respectively. Practical application studies confirmed their efficacy for rapid CIP detection in milk samples, establishing a novel sensing platform for food safety monitoring. This work provides valuable insights into the multifunctional applications of carbon dots in food chemistry and biomedical fields.