Scholarlink

<p>The detrimental effects of deoxynivalenol (DON) on broiler chickens are well documented; however, studies on laying hens fed diets naturally contaminated with this mycotoxin remain limited. To evaluate the impact of short-term DON exposure, 600 56-week-old Dekalb White laying hens were fed either a marginally contaminated control diet (CON) or a diet containing 2.45&#xa0;mg/kg DON for 16 weeks. Production performance was impaired by DON as early as 8 weeks of exposure. Although no changes were observed in the physical characteristics of the eggshells, mRNA expression analyses revealed disruptions in calcium and phosphorus metabolism. Despite similar egg production between treatments, DON exposure led to degeneration of primordial, primary, and large white follicles. Metabolomic analysis of the excreta indicated altered lipid metabolism, suggestive of intestinal inflammation, along with increased hydrogen sulphide (H<sub>2</sub>S) levels. In conclusion, short-term exposure to DON negatively affects intestinal function, reproductive health, and feed efficiency in laying hens.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Short-term dietary deoxynivalenol exposure negatively affects performance, intestinal and reproductive functions in laying hens

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月11日

查看全文
  • E. Basili,
  • L. Star,
  • G. Beleva,
  • F. Molist,
  • A. Milanova,
  • R. R. Santos

摘要

The detrimental effects of deoxynivalenol (DON) on broiler chickens are well documented; however, studies on laying hens fed diets naturally contaminated with this mycotoxin remain limited. To evaluate the impact of short-term DON exposure, 600 56-week-old Dekalb White laying hens were fed either a marginally contaminated control diet (CON) or a diet containing 2.45 mg/kg DON for 16 weeks. Production performance was impaired by DON as early as 8 weeks of exposure. Although no changes were observed in the physical characteristics of the eggshells, mRNA expression analyses revealed disruptions in calcium and phosphorus metabolism. Despite similar egg production between treatments, DON exposure led to degeneration of primordial, primary, and large white follicles. Metabolomic analysis of the excreta indicated altered lipid metabolism, suggestive of intestinal inflammation, along with increased hydrogen sulphide (H2S) levels. In conclusion, short-term exposure to DON negatively affects intestinal function, reproductive health, and feed efficiency in laying hens.