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<p>The signal to noise ratio (SNR) is a key performance metric of an imaging instrument. Here we describe the characterisation of SNR of a custom 2-photon microscope and compare the SNR performance of our microscope with selected commercial 2-photon microscopes. The methodology described in this paper can serve as guidance for others wishing to characterise and benchmark their 2-photon or other point-scanning microscopes.</p>

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Characterisation of the signal to noise ratio of 2-photon microscopes

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月26日

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  • Radek Macháň,
  • Shau Poh Chong,
  • Khee Leong Lee,
  • Peter Török

摘要

The signal to noise ratio (SNR) is a key performance metric of an imaging instrument. Here we describe the characterisation of SNR of a custom 2-photon microscope and compare the SNR performance of our microscope with selected commercial 2-photon microscopes. The methodology described in this paper can serve as guidance for others wishing to characterise and benchmark their 2-photon or other point-scanning microscopes.