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<p>To investigate the best combination of parameters by changing the collimator and increment in the volumetric modulated arc therapy after modified radical mastectomy for breast cancer. Ten patients with left breast cancer and ten patients with right breast cancer who underwent modified radical mastectomy were selected in our research cohort. Treatment plans were established utilizing the 3-arc beam configuration spanning 240 degrees. The collimator angle was systematically adjusted in increments of 10 degrees, ranging from − 90 to 90 degrees. Additionally, increment values of 10, 20, 30, and 40 were employed for each corresponding collimator angle. All other planning parameters remained constant across the plans. Finally the impact of different values was analyzed in terms of plan quality and execution efficiency. Regarding the dose distribution within the target and the ipsilateral lung, the optimal collimator angles were observed to range from − 60 to 30 degrees for the left breast and from − 30 to 60 degrees for the right breast. As for the increment value, 10 yielded the optimal outcome, 40 resulted in the least desirable outcome, and 20 and 30 demonstrated a balanced effect between 10 and 40. In terms of execution efficiency and treatment complexity, the impact of the collimator angle on the results exhibits symmetric distribution, and the most favorable collimator angle approaches 0 degrees. Additionally, with a gradual increase in the collimator angle, the execution efficiency diminishes while the complexity correspondingly increases. In the context of treatment planning following modified radical mastectomy for left and right breast cancer, optimal collimator angles fall within the ± 30-degree range, while increment values of 20 and 30 degrees yielded the best overall outcomes, ensuring the attainment of the prescribed dose while accounting for execution efficiency and treatment complexity.</p>

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The impact of collimator angle and increment on volumetric modulated arc therapy after modified radical mastectomy for breast cancer

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月29日

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  • Haiyang Wang,
  • Yifei Pi,
  • Chunbo Liu,
  • Xiaoxiao Zuo,
  • Xin Wang,
  • Bin Han,
  • Xi Pei,
  • Ran Lv,
  • Xie George Xu,
  • Chengzhang Long,
  • Yuexin Guo,
  • Panfeng Wang

摘要

To investigate the best combination of parameters by changing the collimator and increment in the volumetric modulated arc therapy after modified radical mastectomy for breast cancer. Ten patients with left breast cancer and ten patients with right breast cancer who underwent modified radical mastectomy were selected in our research cohort. Treatment plans were established utilizing the 3-arc beam configuration spanning 240 degrees. The collimator angle was systematically adjusted in increments of 10 degrees, ranging from − 90 to 90 degrees. Additionally, increment values of 10, 20, 30, and 40 were employed for each corresponding collimator angle. All other planning parameters remained constant across the plans. Finally the impact of different values was analyzed in terms of plan quality and execution efficiency. Regarding the dose distribution within the target and the ipsilateral lung, the optimal collimator angles were observed to range from − 60 to 30 degrees for the left breast and from − 30 to 60 degrees for the right breast. As for the increment value, 10 yielded the optimal outcome, 40 resulted in the least desirable outcome, and 20 and 30 demonstrated a balanced effect between 10 and 40. In terms of execution efficiency and treatment complexity, the impact of the collimator angle on the results exhibits symmetric distribution, and the most favorable collimator angle approaches 0 degrees. Additionally, with a gradual increase in the collimator angle, the execution efficiency diminishes while the complexity correspondingly increases. In the context of treatment planning following modified radical mastectomy for left and right breast cancer, optimal collimator angles fall within the ± 30-degree range, while increment values of 20 and 30 degrees yielded the best overall outcomes, ensuring the attainment of the prescribed dose while accounting for execution efficiency and treatment complexity.