Scholarlink

<p>Child maltreatment adversely affects brain development, resulting in vulnerabilities in brain structure and function connectivity, as well as various psychiatric disorders. However, the relationship between structural changes in auditory-related regions and auditory function remains unclear. Therefore, this study investigated the relationship between auditory frequencies associated with brain atypicality and child maltreatment. T1-weighted magnetic resonance imaging (MRI) and functional MRI were used to assess differences in gray matter volume (GMV) and functional connectivity (FC) in maltreated children (<i>n</i> = 19) compared to those of no maltreatment history (<i>n</i> = 38) participants. This case–control study focused on the left middle temporal gyrus (L.MTG), a key region in speech perception, and its connectivity with the right temporal pole (R.TP). Additionally, the study analyzed the relationship between these neural alterations and auditory thresholds at pivotal frequencies relevant to speech perception and measures of speech reception thresholds. Maltreatment-related neurodevelopmental adaptations affected GMV (L.MTG; <i>P</i> &lt; 0.001 for peak level, family-wise error [FWE] corrected <i>P</i> = 0.038 for cluster level) and FC (L.MTG-R.TP; <i>P</i> &lt; 0.001 for peak level, FWE corrected <i>P</i> = 0.013 for the cluster level), potentially influencing how abused children process auditory and emotional information. These alterations may have long-term consequences on speech perception, emotional recognition, and social communication. Elucidating these mechanisms will contribute to developing effective therapeutic strategies to improve social and emotional outcomes in maltreated individuals.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Structural and functional atypicality in the temporal cortex are associated with auditory perception in maltreated children

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月2日

查看全文
  • Natasha Y. S. Kawata,
  • Takashi X. Fujisawa,
  • Akiko Yao,
  • Hidehiko Okazawa,
  • Akemi Tomoda

摘要

Child maltreatment adversely affects brain development, resulting in vulnerabilities in brain structure and function connectivity, as well as various psychiatric disorders. However, the relationship between structural changes in auditory-related regions and auditory function remains unclear. Therefore, this study investigated the relationship between auditory frequencies associated with brain atypicality and child maltreatment. T1-weighted magnetic resonance imaging (MRI) and functional MRI were used to assess differences in gray matter volume (GMV) and functional connectivity (FC) in maltreated children (n = 19) compared to those of no maltreatment history (n = 38) participants. This case–control study focused on the left middle temporal gyrus (L.MTG), a key region in speech perception, and its connectivity with the right temporal pole (R.TP). Additionally, the study analyzed the relationship between these neural alterations and auditory thresholds at pivotal frequencies relevant to speech perception and measures of speech reception thresholds. Maltreatment-related neurodevelopmental adaptations affected GMV (L.MTG; P < 0.001 for peak level, family-wise error [FWE] corrected P = 0.038 for cluster level) and FC (L.MTG-R.TP; P < 0.001 for peak level, FWE corrected P = 0.013 for the cluster level), potentially influencing how abused children process auditory and emotional information. These alterations may have long-term consequences on speech perception, emotional recognition, and social communication. Elucidating these mechanisms will contribute to developing effective therapeutic strategies to improve social and emotional outcomes in maltreated individuals.