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<p>The level and predictors of medication adherence have not been given attention among populations for whom the cost of treatment is not a concern, especially in the Ghanaian healthcare setting. This study compared generalised linear models to determine the factors associated with adherence to treatment among hypertensive patients with a workplace policy that offers cost-free access in Ghana. We conducted a cross-sectional descriptive study to investigate the level of adherence and factors that influence practice among hypertensive patients with cost-free access to treatment. A total of 254 respondents were conveniently sampled and administered a questionnaire. The predictors of treatment adherence were assessed using Bivariate and generalised linear models (logistic and complementary log–log regression models). The complementary log–log regression model outperformed the logistic regression model in fitting the relationships in the data, by reporting lower AIC and BIC, and higher Nagelkerke and Cox and Snell pseudo-R-squared values. Most (88.9%) respondents scored low adherence, and only 11.1% adhered to treatment. The factors that affect adherence to hypertension medication included age (ARR = 8.58, 95%CI 1.23–83.28, <i>p-value</i> = 0.031), sex (ARR = 0.19, 95%CI 0.03–0.91, <i>p-value</i> = 0.042), location (ARR = 10.78, 95%CI 2.01–79.76, <i>p-value</i> = 0.007), busy schedule (ARR = 0.03, 95%CI 0.00–0.30, <i>p-value</i> = 0.016), time spent (ARR = 0.05, 95%CI 0.00–0.28, <i>p-value</i> = 0.002) and accessibility (ARR = 17.89, 95%CI 4.03–112.38, <i>p-value</i> &lt; 0.001). The high level of non-adherence to treatment among patients, even when the cost of treatment is not a barrier, could contribute to overall treatment outcomes. Despite cost-free access, adherence remains low, highlighting the need for further investigation into non-cost barriers affecting treatment compliance. In addition, there is a need to design and implement measures to improve adherence among patients with hypertension in the country.</p>

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The predictors of treatment adherence among hypertensive patients with cost-free access

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月30日

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  • Felix Kwasi Nyande,
  • Kennedy Diema Konlan,
  • Linda Serwaa Asiamah,
  • Vivian Boateng,
  • Joyce Gbeamir,
  • Veronica Dankwah,
  • Robert Quaicoe,
  • David Adedia

摘要

The level and predictors of medication adherence have not been given attention among populations for whom the cost of treatment is not a concern, especially in the Ghanaian healthcare setting. This study compared generalised linear models to determine the factors associated with adherence to treatment among hypertensive patients with a workplace policy that offers cost-free access in Ghana. We conducted a cross-sectional descriptive study to investigate the level of adherence and factors that influence practice among hypertensive patients with cost-free access to treatment. A total of 254 respondents were conveniently sampled and administered a questionnaire. The predictors of treatment adherence were assessed using Bivariate and generalised linear models (logistic and complementary log–log regression models). The complementary log–log regression model outperformed the logistic regression model in fitting the relationships in the data, by reporting lower AIC and BIC, and higher Nagelkerke and Cox and Snell pseudo-R-squared values. Most (88.9%) respondents scored low adherence, and only 11.1% adhered to treatment. The factors that affect adherence to hypertension medication included age (ARR = 8.58, 95%CI 1.23–83.28, p-value = 0.031), sex (ARR = 0.19, 95%CI 0.03–0.91, p-value = 0.042), location (ARR = 10.78, 95%CI 2.01–79.76, p-value = 0.007), busy schedule (ARR = 0.03, 95%CI 0.00–0.30, p-value = 0.016), time spent (ARR = 0.05, 95%CI 0.00–0.28, p-value = 0.002) and accessibility (ARR = 17.89, 95%CI 4.03–112.38, p-value < 0.001). The high level of non-adherence to treatment among patients, even when the cost of treatment is not a barrier, could contribute to overall treatment outcomes. Despite cost-free access, adherence remains low, highlighting the need for further investigation into non-cost barriers affecting treatment compliance. In addition, there is a need to design and implement measures to improve adherence among patients with hypertension in the country.