The search for new gravity-like interactions at the sub-millimeter scale is a compelling area of research, with important implications for the understanding of classical gravity and its connections with quantum physics. We report improved constraints on Yukawa-type interactions in the \(10\,\mathrm {\mu m}\) regime using optically levitated dielectric microspheres as test masses. The search is performed, for the first time, sensing multiple spatial components of the force vector, and with sensitivity improved by a factor of \(\sim 100\) with respect to previous measurements using the same technique. The resulting upper limit on the strength of a hypothetical new force is \(10^7\) at a Yukawa range \(\lambda \simeq 5\;\mu\) m and close to \(10^6\) for \(\lambda \gtrsim 10\;\mu\) m. This result also advances our efforts to measure gravitational effects using micrometer-size objects, with important implications for embryonic ideas to investigate the quantum nature of gravity.
