Scholarlink

<p>To explore the value of applying the MRI-based radiomic nomogram for predicting lymph node metastasis (LNM) in rectal cancer (RC). This retrospective analysis used data from 430 patients with RC from two medical centers. The patients were categorized into the LNM negative (LNM−) and LNM positive (LNM+) according to their surgical pathology results. We developed a physician model by selecting clinical independent predictors through physician assessments. Additionally, we developed deep learning radscore (DLRS) models by extracting deep features from multiparametric MRI (mpMRI) images. A nomogram model was constructed by combining the physician model and DLRS models. Among the patients, 192 (44.65%, 192/430) experienced LNM+. Six prediction models were developed, namely the physician model, three sequence models, the DLRS, and the nomogram. The physician model achieved AUC of the receiver operating characteristic (ROC) values of 0.78, 0.79, and 0.7, whereas the sequence models, DLRS model, and nomogram model achieved AUC values ranging from 0.83 to 0.99. The predictive performance of the DLRS and nomogram models was superior to that of the physician model. DLRS and nomogram models based on mpMRI provided higher accuracy in predicting LNM status in patients with RC than the other models.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Novel deep learning algorithm based MRI radiomics for predicting lymph node metastases in rectal cancer

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月9日

查看全文
  • Weiqun Ao,
  • Sikai Wu,
  • Neng Wang,
  • Guoqun Mao,
  • Jian Wang,
  • Jinwen Hu,
  • Xiaoyu Han,
  • Shuitang Deng

摘要

To explore the value of applying the MRI-based radiomic nomogram for predicting lymph node metastasis (LNM) in rectal cancer (RC). This retrospective analysis used data from 430 patients with RC from two medical centers. The patients were categorized into the LNM negative (LNM−) and LNM positive (LNM+) according to their surgical pathology results. We developed a physician model by selecting clinical independent predictors through physician assessments. Additionally, we developed deep learning radscore (DLRS) models by extracting deep features from multiparametric MRI (mpMRI) images. A nomogram model was constructed by combining the physician model and DLRS models. Among the patients, 192 (44.65%, 192/430) experienced LNM+. Six prediction models were developed, namely the physician model, three sequence models, the DLRS, and the nomogram. The physician model achieved AUC of the receiver operating characteristic (ROC) values of 0.78, 0.79, and 0.7, whereas the sequence models, DLRS model, and nomogram model achieved AUC values ranging from 0.83 to 0.99. The predictive performance of the DLRS and nomogram models was superior to that of the physician model. DLRS and nomogram models based on mpMRI provided higher accuracy in predicting LNM status in patients with RC than the other models.