Scholarlink

<p>This study presents a patient-specific computational analysis of hemodynamic alterations induced by stent-assisted deformation in five cerebral aneurysm models. Using high-fidelity geometrical reconstructions and computational fluid dynamics (CFD) simulations, the effects of parent vessel deformation on Wall Shear Stress (WSS), Oscillatory Shear Index (OSI), and blood flow velocity were systematically evaluated across distinct aneurysm geometries. The results demonstrate that each model exhibited a unique hemodynamic response to deformation. Model A showed an increase in WSS and OSI, indicating enhanced flow instability; Model B remained largely insensitive, displaying negligible hemodynamic variation; Model C experienced reductions in OSI and velocity, suggesting a stabilized intra-aneurysmal environment; Model D revealed a gradual decrease and redistribution of axial velocity, reflecting attenuation of inflow momentum; and Model E exhibited a pronounced redirection of the inflow jet and asymmetric velocity field, accompanied by a moderate decline in flow magnitude. Overall, these findings emphasize the critical role of aneurysm morphology and vessel curvature in modulating post-treatment hemodynamics and reinforce the need for patient-specific computational modeling to guide stent design and placement for improved clinical outcomes in cerebral aneurysm management.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Hemodynamic response to stent-induced aneurysm deformation in patient-specific internal carotid artery cases: A computational study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月4日

查看全文
  • Wajdi Rajhi,
  • Zakarya Ahmed,
  • Ali Basem,
  • As’ad Alizadeh,
  • Shaymaa Abed Hussein,
  • Husam Rajab,
  • Borhen Louhichi,
  • Walid Aich

摘要

This study presents a patient-specific computational analysis of hemodynamic alterations induced by stent-assisted deformation in five cerebral aneurysm models. Using high-fidelity geometrical reconstructions and computational fluid dynamics (CFD) simulations, the effects of parent vessel deformation on Wall Shear Stress (WSS), Oscillatory Shear Index (OSI), and blood flow velocity were systematically evaluated across distinct aneurysm geometries. The results demonstrate that each model exhibited a unique hemodynamic response to deformation. Model A showed an increase in WSS and OSI, indicating enhanced flow instability; Model B remained largely insensitive, displaying negligible hemodynamic variation; Model C experienced reductions in OSI and velocity, suggesting a stabilized intra-aneurysmal environment; Model D revealed a gradual decrease and redistribution of axial velocity, reflecting attenuation of inflow momentum; and Model E exhibited a pronounced redirection of the inflow jet and asymmetric velocity field, accompanied by a moderate decline in flow magnitude. Overall, these findings emphasize the critical role of aneurysm morphology and vessel curvature in modulating post-treatment hemodynamics and reinforce the need for patient-specific computational modeling to guide stent design and placement for improved clinical outcomes in cerebral aneurysm management.