Scholarlink

<p>To determine the critical blink frequency threshold for maintaining tear film stability in young participants with dry eye symptoms. In this two-phase study, 45 young participants (aged 19–28&#xa0;years) with dry eye symptoms (Ocular Surface Disease Index, OSDI ≥ 13) underwent spontaneous blink measurements (Phase 1) and controlled blink experiments (Phase 2: spontaneous, 10 blinks/min, and 20 blinks/min). Tear meniscus height (TMH), non-invasive tear break-up time (BUT), bulbar redness (BR), and Standard Patient Evaluation of Eye Dryness (SANDE) scores were obtained and analyzed. Spontaneous blink frequency (27.75 ± 14.43 blinks/min) positively correlated with TMH (r = 0.48, <i>p</i> &lt; 0.01). Reducing blink frequency to 10 blinks/min significantly worsened TMH (<i>p</i> = 0.0002), BUT (<i>p</i> &lt; 0.0001), BR (<i>p</i> &lt; 0.0001), and SANDE scores (<i>p</i> &lt; 0.0001) compared to spontaneous blinking. No differences were found between spontaneous blinking and controlled 20 blinks/min. A blink frequency threshold of ≥ 20 blinks/min is critical for stabilizing tear film in young participants with dry eye symptoms. Interventions targeting blink frequency may mitigate symptoms exacerbated by digital device use.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Identification of a blink frequency threshold for maintaining tear film stability in young adults with dry eye symptoms

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月27日

查看全文
  • Yawei Chai,
  • Mingrui Cheng,
  • Xinhua Liu,
  • Yiteng Lu,
  • Xingyu Zhu,
  • Yuqing Wu,
  • Qihua Le,
  • Jiaxu Hong

摘要

To determine the critical blink frequency threshold for maintaining tear film stability in young participants with dry eye symptoms. In this two-phase study, 45 young participants (aged 19–28 years) with dry eye symptoms (Ocular Surface Disease Index, OSDI ≥ 13) underwent spontaneous blink measurements (Phase 1) and controlled blink experiments (Phase 2: spontaneous, 10 blinks/min, and 20 blinks/min). Tear meniscus height (TMH), non-invasive tear break-up time (BUT), bulbar redness (BR), and Standard Patient Evaluation of Eye Dryness (SANDE) scores were obtained and analyzed. Spontaneous blink frequency (27.75 ± 14.43 blinks/min) positively correlated with TMH (r = 0.48, p < 0.01). Reducing blink frequency to 10 blinks/min significantly worsened TMH (p = 0.0002), BUT (p < 0.0001), BR (p < 0.0001), and SANDE scores (p < 0.0001) compared to spontaneous blinking. No differences were found between spontaneous blinking and controlled 20 blinks/min. A blink frequency threshold of ≥ 20 blinks/min is critical for stabilizing tear film in young participants with dry eye symptoms. Interventions targeting blink frequency may mitigate symptoms exacerbated by digital device use.