<p>Individuals with childhood-onset divergent neurological development, such as autism or Attention-Deficit Hyperactivity Disorder (ADHD), may live a good life according to objectively or subjectively determined standards. Yet, most research has focused on deficits and risks for negative outcomes. This international study forms part of a larger project examining the factors contributing to well-being, mental health, and functioning outcomes in neurodivergent populations using the World Health Organization (WHO) International Classification of Functioning (ICF). Following ICF research branch methodology, 198 professionals were surveyed on the factors that they believe are important for risk and resilience in neurodivergent populations and linked responses to ICF nomenclature using a standardized linking process. A range of bio-psycho-social factors perceived to be important for risk and resilience in neurodivergent populations were identified, including temperament and personality, emotional functions, the structure of the brain, financial status, recreation and leisure, and the immediate family. Most factors identified were environmental or related to activity and participation. Findings add to the limited literature on resilience in neurodivergent populations. We identify risk- and resilience-inducing factors that operate in the context of neurodivergence across the lifespan. These serve as candidates for future investigation and provide targets for intervention and social participation support.</p>