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<p>people with diabetes mellitus frequently develop diabetic ketoacidosis, which greatly increases mortality. However, there is scarcity of up-to-date data on the recurrence of diabetic ketoacidosis and predictors among individuals with diabetes mellitus in Ethiopia. An institution-based retrospective follow up study design was conducted. STATA software was used for the final analysis of the data. Negative binomial regression model was used at a 95% confidence level. Statistical significance of the predictor on outcome variables was declared at P-value &lt; 0.05. In this study, 378 charts were reviewed. The mean recurrence of diabetic ketoacidosis was 0.63 (0–4) and among 378 DM patients, 135 (35.71%) had at least one DKA episode per one year. Being female (AIRR = 1.57, 95% CI 1.18–2.07), type 1 diabetes mellitus (AIRR = 2.70, 95% CI 1.75–4.35), longer duration of diabetes mellitus (AIRR = 2.36, 95% CI 1.27–2.91), acute infection (AIRR = 4.33, 95% CI 2.75–6.83), comorbidity (AIRR = 1.58, 95% CI 1.18–2.09), and mixed type of treatment (AIRR = 2.04, 95% CI 1.30–3.2) were risk factors whereas injection type of treatment (AIRR = 0.65, 95% CI 0.44–0.96) and medication compliance (AIRR = 0.23, 95% CI 0.17–0.31) were reduce the risk of recurrence of diabetic ketoacidosis. Clinicians should prioritize management of patients with risk factors of diabetic ketoacidosis recurrence.</p>

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Recurrence and predictors of diabetic ketoacidosis among individuals with diabetes mellitus in public hospitals of Bahir Dar city, Ethiopia

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月18日

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  • Tadios Lidetu,
  • Asnaku Tadlo,
  • Gebiyaw Wudie,
  • Beselam Gizachew,
  • Desiyalew Habtamu Tamiru

摘要

people with diabetes mellitus frequently develop diabetic ketoacidosis, which greatly increases mortality. However, there is scarcity of up-to-date data on the recurrence of diabetic ketoacidosis and predictors among individuals with diabetes mellitus in Ethiopia. An institution-based retrospective follow up study design was conducted. STATA software was used for the final analysis of the data. Negative binomial regression model was used at a 95% confidence level. Statistical significance of the predictor on outcome variables was declared at P-value < 0.05. In this study, 378 charts were reviewed. The mean recurrence of diabetic ketoacidosis was 0.63 (0–4) and among 378 DM patients, 135 (35.71%) had at least one DKA episode per one year. Being female (AIRR = 1.57, 95% CI 1.18–2.07), type 1 diabetes mellitus (AIRR = 2.70, 95% CI 1.75–4.35), longer duration of diabetes mellitus (AIRR = 2.36, 95% CI 1.27–2.91), acute infection (AIRR = 4.33, 95% CI 2.75–6.83), comorbidity (AIRR = 1.58, 95% CI 1.18–2.09), and mixed type of treatment (AIRR = 2.04, 95% CI 1.30–3.2) were risk factors whereas injection type of treatment (AIRR = 0.65, 95% CI 0.44–0.96) and medication compliance (AIRR = 0.23, 95% CI 0.17–0.31) were reduce the risk of recurrence of diabetic ketoacidosis. Clinicians should prioritize management of patients with risk factors of diabetic ketoacidosis recurrence.