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<p>Periodontal diseases remain highly prevalent across age groups, often aggravated by poor oral hygiene, occlusal anomalies, and defective restorations. This study evaluated the effectiveness of Art-Dentale Expert mouthwash against major periodontopathogens in patients with mild chronic generalized periodontitis (CGP) using PCR diagnostics. Thirty-nine patients with CGP were randomized into a main group (Art-Dentale Expert) and a control group (Chlorhexidine). Gingival pocket samples were collected before treatment and at 7 days, 1 month, and 6 months. Four periodontopathogens (P. gingivalis, T. forsythia, T. denticola, and P. intermedia) were analyzed. The results obtained were processed statistically. Both rinses significantly reduced P. gingivalis and T. forsythia at 7 days, with Chlorhexidine showing a sharper initial decline in P. gingivalis. At 6 months, P. intermedia was completely absent in the Art-Dentale Expert group (<i>p</i> = 0.0209), whereas it persisted in 10% of controls. Art-Dentale Expert demonstrated sustained efficacy, particularly against T. denticola and P. intermedia. These findings support its role as an effective adjunct in periodontal therapy.</p>

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Of the article: Microbiological assessment of a herbal mouth rinse for treating chronic generalized periodontitis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月31日

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  • Svetlana Razumova,
  • Sergey Panov,
  • Anna Marakhova,
  • Irina Koroleva,
  • Ekaterina Mikhailova,
  • Anzhela Brago,
  • Haydar Barakat

摘要

Periodontal diseases remain highly prevalent across age groups, often aggravated by poor oral hygiene, occlusal anomalies, and defective restorations. This study evaluated the effectiveness of Art-Dentale Expert mouthwash against major periodontopathogens in patients with mild chronic generalized periodontitis (CGP) using PCR diagnostics. Thirty-nine patients with CGP were randomized into a main group (Art-Dentale Expert) and a control group (Chlorhexidine). Gingival pocket samples were collected before treatment and at 7 days, 1 month, and 6 months. Four periodontopathogens (P. gingivalis, T. forsythia, T. denticola, and P. intermedia) were analyzed. The results obtained were processed statistically. Both rinses significantly reduced P. gingivalis and T. forsythia at 7 days, with Chlorhexidine showing a sharper initial decline in P. gingivalis. At 6 months, P. intermedia was completely absent in the Art-Dentale Expert group (p = 0.0209), whereas it persisted in 10% of controls. Art-Dentale Expert demonstrated sustained efficacy, particularly against T. denticola and P. intermedia. These findings support its role as an effective adjunct in periodontal therapy.