Predictive value of tidal volume and peak inspiratory pressure in normal frequency jet ventilation
摘要
Normal frequency jet ventilation (NFJV) is commonly used during rigid bronchoscopy; however, airway opening does not reliably measure or predict tidal volume (VT) or peak inspiratory pressure (PIP). This study aimed to investigate the comprehensive effects on VT and PIP concerning key variables, including driving pressure (DPpipeline), frequency (Fjet), needle inner diameter (IDneedle), and lung dynamic compliance (Cdyn). Three jet needles (N1, N2, and N3) with different internal diameters (1.2–1.9 mm) were used to deliver jet ventilation via a rigid bronchoscope at DPs of 0.6–1.6 bar and frequencies of 10–60 min⁻¹. Airway pressure (Paw) was measured near the tracheal prominence of the simulated lung. Expiratory gas flow was diverted into a dedicated collection chamber fitted with a solenoid valve over a one-minute period, and the collected volume was measured as minute volume (MV). ①. Statistical analysis of the two lung models revealed consistent findings: both VT and PIP values in N2 and N3 demonstrated statistically significant differences compared to N1 (P < 0.05). Additionally, significant differences in the VT and PIP values were observed between N2 and N3 (P < 0.05). ②. Multiple linear regression analyses indicated that DPpipeline, Fjet, and IDneedle had statistically significant effects on VT and PIP (P < 0.05). Conversely, Cdyn significantly affected VT (P < 0.05) but did not have a significant impact on PIP (P > 0.05). The primary variables exerting a significant influence on VT and PIP were DPpipeline, Fjet, and IDneedle. Furthermore, Cdyn significantly affected VT but not PIP. VT and PIP can be accurately predicted using regression equations.