Postdischarge participation and functional outcomes across three common stroke subtypes based on the exploratory retrospective study
摘要
This study investigated the impact of stroke subtypes—ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH)—on long-term participation and functional outcomes 12 months postdischarge. Datasets from two prospective studies were retrospectively analyzed for adults with these stroke subtypes who received inpatient rehabilitation. Outcomes, including Participation Measure-3 Domains, 4 Dimensions (PM-3D4D), Activity Measure for Post-Acute Care, EuroQol 5-Dimension 3-Level, and Montreal Cognitive Assessment scores, were tracked from hospital discharge up to 12 months. Among 646 patients (256 women, mean age 56.6 years), patients with IS (n = 335) and ICH (n = 288) showed similar postdischarge recovery patterns, whereas patients with SAH (n = 23) generally had poorer outcomes at 12 months. The most substantial difference was observed in productivity frequency scores (a PM-3D4D subdomain), with SAH group exhibiting significantly lower scores (0.04 [0–0.09]) compared to IS (0.39 [0.33–0.45]) and ICH (0.44 [0.37–0.51]) groups (P < 0.001). After adjusting for age and sex, better activity function at discharge was found to be an independent predictor of higher PM-3D4D scores 12 months postdischarge. These findings highlight that SAH is associated with poorer long-term outcomes compared to other subtypes, demonstrate subtype-specific profiles, and suggest activity function as a key target for inpatient rehabilitation to enhance participation postdischarge.