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<p>Transcranial Direct Current Stimulation (tDCS) has been employed to enhance executive control (EC), thereby improving cognitive functions and mental health. However, the effects of tDCS on EC remain inconclusive, and the mechanisms involved in its impact on baseline and conflict processing are not well understood. This study applied high-definition tDCS (HD-tDCS) to the left dorsolateral prefrontal cortex DLPFC) to investigate the distinct effects of tDCS on baseline and conflict processing. Compared to the sham group, tDCS significantly reduced reaction time variability in both conditions and decreased mean reaction time and error rate in the conflict condition. These findings demonstrate significant enhancements in general behavioral stability and conflict processing respectively. This study demonstrates a significant enhancement of tDCS on EC, elucidating the dual mechanisms of tDCS in modulating the baseline state and EC, providing valuable insights into the mechanisms of tDCS intervention on cognitive functions.</p>

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HD-tDCS improves conflict processing and general behavioral stability

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月17日

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  • Ronghan Liu,
  • Miao Wang,
  • Qiang Liu,
  • Xiujuan Jing,
  • Qiang Hao,
  • Hang Yu,
  • Yifeng Wang

摘要

Transcranial Direct Current Stimulation (tDCS) has been employed to enhance executive control (EC), thereby improving cognitive functions and mental health. However, the effects of tDCS on EC remain inconclusive, and the mechanisms involved in its impact on baseline and conflict processing are not well understood. This study applied high-definition tDCS (HD-tDCS) to the left dorsolateral prefrontal cortex DLPFC) to investigate the distinct effects of tDCS on baseline and conflict processing. Compared to the sham group, tDCS significantly reduced reaction time variability in both conditions and decreased mean reaction time and error rate in the conflict condition. These findings demonstrate significant enhancements in general behavioral stability and conflict processing respectively. This study demonstrates a significant enhancement of tDCS on EC, elucidating the dual mechanisms of tDCS in modulating the baseline state and EC, providing valuable insights into the mechanisms of tDCS intervention on cognitive functions.