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<p>Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular complications. While coffee, tea, and caffeine consumption have been linked to various health benefits, their relationship with CKD remains unclear. We conducted a cross-sectional analysis of NHANES 1999–2018 data, including 49,827 participants, assessing dietary intake through two 24-hour recalls and determining CKD status via the CKD-EPI equation. Our results showed that after adjusting for covariates, higher coffee consumption (&gt; 352.5&#xa0;g/day) was associated with lower odds of CKD (OR 0.760, 95% CI 0.701–0.823), as was tea consumption (OR 0.913, 95% CI 0.843–0.89). The highest tertile of caffeine consumption also showed a significantly reduced odds of CKD (OR 0.734, 95% CI 0.674–0.799). These findings suggest that coffee, tea, and caffeine consumption may be associated with better renal function, highlighting potential dietary strategies for CKD prevention.</p>

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Association between coffee and caffeine consumption and chronic kidney disease

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月12日

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  • Panpan Gao,
  • Xinrong Ji,
  • Weiwei Wang,
  • Yao Chen,
  • Zhan Gao,
  • Zengli Yu

摘要

Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular complications. While coffee, tea, and caffeine consumption have been linked to various health benefits, their relationship with CKD remains unclear. We conducted a cross-sectional analysis of NHANES 1999–2018 data, including 49,827 participants, assessing dietary intake through two 24-hour recalls and determining CKD status via the CKD-EPI equation. Our results showed that after adjusting for covariates, higher coffee consumption (> 352.5 g/day) was associated with lower odds of CKD (OR 0.760, 95% CI 0.701–0.823), as was tea consumption (OR 0.913, 95% CI 0.843–0.89). The highest tertile of caffeine consumption also showed a significantly reduced odds of CKD (OR 0.734, 95% CI 0.674–0.799). These findings suggest that coffee, tea, and caffeine consumption may be associated with better renal function, highlighting potential dietary strategies for CKD prevention.