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<p>Insomnia is common among university students and is associated with mental health problems. Students often have irregular day/night rhythms, which contribute to circadian rhythm disruptions. This open pilot study investigated the feasibility, acceptability, and preliminary effectiveness of a 5-week digital guided self-help intervention in university students with self-reported insomnia. The intervention is based on cognitive behavioural therapy for insomnia with specific emphasis on the biological clock (<i>‘i-Sleep &amp; BioClock’</i>). We assessed feasibility and acceptability. Pre- to post-intervention (7-week) changes in insomnia, depression, anxiety, chronotype, and quality of life were evaluated. Of 101 included students, 81 accessed the platform, 41 initiated the intervention, and 13 completed the intervention. Post-test response was 39%. Students rated the intervention with good acceptability and the platform with excellent usability. Study completers (<i>n</i> = 39) showed large improvements in insomnia severity (<i>p</i> &lt; 0.001, <i>d</i> = 1.04), and moderate improvements in depression (<i>p</i> &lt; 0.001, <i>d</i> = 0.63), anxiety (<i>p</i> &lt; 0.001, <i>d</i> = 0.35), and functioning (<i>p</i> &lt; 0.001, <i>d</i> = 0.56). No significant changes were found in quality of life (<i>p</i> = 0.07, <i>d</i> = 0.19). To summarize, the intervention had low uptake but moderate adherence and fairly good acceptability along with important improvements in sleep, mental health, and functioning.</p><p><b>Trial registration:</b> ClinicalTrials.gov: NCT05363995.</p>

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Open pilot study of a guided digital self-help intervention targeting sleep and the biological clock in university students using a pre-test post-test design

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月1日

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  • Laura M. Pape,
  • Niki Antypa,
  • Philip Spinhoven,
  • Annemieke van Straten,
  • Sascha Y. Struijs,
  • Sascha Struijs,
  • Nadia Garnefski,
  • Vivian Kraaij,
  • Elske Salemink,
  • Petra Hurks,
  • Marilisa Boffo,
  • Danielle Remmerswaal,
  • Reinout Wiers,
  • Claudia van der Heijde,
  • Lisa Klinkenberg,
  • Monique de Bruijn-Smolders,
  • Jessica Nooij

摘要

Insomnia is common among university students and is associated with mental health problems. Students often have irregular day/night rhythms, which contribute to circadian rhythm disruptions. This open pilot study investigated the feasibility, acceptability, and preliminary effectiveness of a 5-week digital guided self-help intervention in university students with self-reported insomnia. The intervention is based on cognitive behavioural therapy for insomnia with specific emphasis on the biological clock (‘i-Sleep & BioClock’). We assessed feasibility and acceptability. Pre- to post-intervention (7-week) changes in insomnia, depression, anxiety, chronotype, and quality of life were evaluated. Of 101 included students, 81 accessed the platform, 41 initiated the intervention, and 13 completed the intervention. Post-test response was 39%. Students rated the intervention with good acceptability and the platform with excellent usability. Study completers (n = 39) showed large improvements in insomnia severity (p < 0.001, d = 1.04), and moderate improvements in depression (p < 0.001, d = 0.63), anxiety (p < 0.001, d = 0.35), and functioning (p < 0.001, d = 0.56). No significant changes were found in quality of life (p = 0.07, d = 0.19). To summarize, the intervention had low uptake but moderate adherence and fairly good acceptability along with important improvements in sleep, mental health, and functioning.

Trial registration: ClinicalTrials.gov: NCT05363995.