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<p>Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transmitting mosquitoes feed and rest outdoors. To target these, we have developed an alternative application method that exploits the lethality of transgenic fungi as a sexually transmitted mosquito disease. This approach has both a wider interdisciplinary significance and important implications for preventing mosquito-borne diseases.</p>

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Transmission of transgenic mosquito-killing fungi during copulation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月16日

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  • Etienne Bilgo,
  • Brian Lovett,
  • Abel Souro Millogo,
  • Issiaka Sare,
  • Edounou Jacques Gnambani,
  • Raymond St. Leger,
  • Abdoulaye Diabaté

摘要

Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transmitting mosquitoes feed and rest outdoors. To target these, we have developed an alternative application method that exploits the lethality of transgenic fungi as a sexually transmitted mosquito disease. This approach has both a wider interdisciplinary significance and important implications for preventing mosquito-borne diseases.