Scholarlink

<p>The brain is a complex system of structure and function. Brain diseases and brain functional abnormalities often involve multiple functionally connected regions, including the deep brain. Studies have shown that multi-target electrical stimulation is more effective than single-target electrical stimulation. However, non-invasive multi-target electromagnetic stimulation, such as multi-target transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) cannot meet the needs of synchronous multi-target accurate electrical stimulation at the deep brain. In this paper, based on the principle of magneto-acoustic coupling and phased array focusing technology, a novel non-invasive multi-target transcranial magneto-acoustic coupling electrical stimulation (multi-target TMAES) method is proposed. A simulation model and experimental system were established. The simulation and experimental results proved that the proposed multi-target TMAES can non-invasively achieve precise focused electrical stimulation of two targets. The average focal point size&#xa0;of each target is 5.1&#xa0;mm. The location and intensity of the multi-target electrical stimulation can be flexibly changed by adjusting the system parameters according to the actual need. It will provide a new and promising tool for the treatment of brain diseases and the study of neural circuits and brain functional connectivity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The simulation and experimental validation of a novel noninvasive multi-target electrical stimulation method

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月11日

查看全文
  • Kai Zhu,
  • Xiaoqing Zhou,
  • Xu Liu,
  • Ren Ma,
  • Mingpeng Wang,
  • Shunqi Zhang,
  • Tao Yin,
  • Zhipeng Liu

摘要

The brain is a complex system of structure and function. Brain diseases and brain functional abnormalities often involve multiple functionally connected regions, including the deep brain. Studies have shown that multi-target electrical stimulation is more effective than single-target electrical stimulation. However, non-invasive multi-target electromagnetic stimulation, such as multi-target transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) cannot meet the needs of synchronous multi-target accurate electrical stimulation at the deep brain. In this paper, based on the principle of magneto-acoustic coupling and phased array focusing technology, a novel non-invasive multi-target transcranial magneto-acoustic coupling electrical stimulation (multi-target TMAES) method is proposed. A simulation model and experimental system were established. The simulation and experimental results proved that the proposed multi-target TMAES can non-invasively achieve precise focused electrical stimulation of two targets. The average focal point size of each target is 5.1 mm. The location and intensity of the multi-target electrical stimulation can be flexibly changed by adjusting the system parameters according to the actual need. It will provide a new and promising tool for the treatment of brain diseases and the study of neural circuits and brain functional connectivity.