<p>Over the last 800,000 years, Earth’s climate has experienced periodic glacial and interglacial cycles driven by orbital parameters, CO₂ concentrations, and ice sheet volumes. To understand how these climate forcing factors influence climate on orbital scales, high-resolution and continuous paleoclimate simulations are crucial. This study employed the CESM1.2.2 Earth System Model for four 800,000-year orbital-accelerated transient climate simulations, including a full-forcing experiment and three single-factor forcing experiments. The results were compared with geological proxy records from various regions, showing good agreement in mid-low latitude monsoon systems, mid-latitude sea surface temperatures, and high-latitude North Atlantic climate variability. However, the model underestimated sea surface temperature fluctuations in the tropics and Southern Hemisphere mid-latitudes. Despite this, it accurately depicted high-latitude climate characteristics. These climate simulation datasets include global annual mean surface temperature and precipitation distributions with a horizontal resolution of 3.75°. Overall, these simulations provide a reliable and verifiable climate dataset, offering strong support for studying the driving mechanisms of past glacial-interglacial climate changes and interpreting long-term climate signals in geological records.</p>