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Sensory and behavioral modulation of thalamic head-direction cells

  • Eduardo Blanco-Hernández,
  • Giuseppe Balsamo,
  • Patricia Preston-Ferrer,
  • Andrea Burgalossi

摘要

Head-direction (HD) neurons are thought to exclusively encode directional heading. In awake mice, we found that sensory stimuli evoked robust short-latency responses in thalamic HD cells, but not in non-HD neurons. The activity of HD cells, but not that of non-HD neurons, was tightly correlated to brain-state fluctuations and dynamically modulated during social interactions. These data point to a new role for the thalamic compass in relaying sensory and behavioral-state information.