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Vitessce: integrative visualization of multimodal and spatially resolved single-cell data

  • Mark S. Keller,
  • Ilan Gold,
  • Chuck McCallum,
  • Trevor Manz,
  • Peter V. Kharchenko,
  • Nils Gehlenborg

摘要

Multiomics technologies with single-cell and spatial resolution make it possible to measure thousands of features across millions of cells. However, visual analysis of high-dimensional transcriptomic, proteomic, genome-mapped and imaging data types simultaneously remains a challenge. Here we describe Vitessce, an interactive web-based visualization framework for exploration of multimodal and spatially resolved single-cell data. We demonstrate integrative visualization of millions of data points, including cell-type annotations, gene expression quantities, spatially resolved transcripts and cell segmentations, across multiple coordinated views. The open-source software is available at http://vitessce.io.