Scholarlink

<p>Oropouche virus (OROV) was reported in Cuba in May 2024 and rapidly spread throughout the country. Here, among 147 reverse-transcription polymerase chain reaction-positive cases identified from May to July 2024, we sequenced 39 whole genomes of OROV. Phylogenetic analysis revealed that all sequences formed a monophyletic cluster nested within the reassortant lineage, named OROV<sub>BR-2015–2025</sub>, which has been circulating extensively in Brazil since 2023. Additional phylogeographic analyses demonstrated that the Cuban subclade probably originated from a single viral introduction from the Brazilian state of Acre in early February 2024, followed by cryptic circulation until its identification in May. The introduction probably occurred in the central region of the country, from which the virus spread and established secondary transmission hubs in the western and eastern regions. These findings underscore the capacity of OROV to spread well beyond South America, which was considered its endemic area of circulation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Spatiotemporal diffusion of the 2024 Oropouche outbreak in Cuba

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月7日

查看全文
  • Rosario Gravier,
  • Melissa M. Perez,
  • Mayling Álvarez,
  • Lissette Pérez,
  • Ana J. Benítez,
  • Denelsys Hernández,
  • Silvia Serrano,
  • José Raúl de Armas,
  • Carilda Peña,
  • Madelaine Rivera,
  • Leticia Franco,
  • Juliana Leite,
  • Lionel Gresh,
  • Jairo Méndez,
  • Víctor Souza,
  • Matilde Mejía,
  • Gonzalo Bello,
  • Ighor Arantes,
  • Sonia Resik,
  • Vivian Kouri,
  • Felipe Gomes Naveca,
  • Maria G. Guzman

摘要

Oropouche virus (OROV) was reported in Cuba in May 2024 and rapidly spread throughout the country. Here, among 147 reverse-transcription polymerase chain reaction-positive cases identified from May to July 2024, we sequenced 39 whole genomes of OROV. Phylogenetic analysis revealed that all sequences formed a monophyletic cluster nested within the reassortant lineage, named OROVBR-2015–2025, which has been circulating extensively in Brazil since 2023. Additional phylogeographic analyses demonstrated that the Cuban subclade probably originated from a single viral introduction from the Brazilian state of Acre in early February 2024, followed by cryptic circulation until its identification in May. The introduction probably occurred in the central region of the country, from which the virus spread and established secondary transmission hubs in the western and eastern regions. These findings underscore the capacity of OROV to spread well beyond South America, which was considered its endemic area of circulation.