Despite advancements in wearable technologies1,2, barriers remain in achieving distributed computation located persistently on the human body. Here a textile fibre computer that monolithically combines analogue sensing, digital memory, processing and communication in a mass of less than 5 g is presented. Enabled by a foldable interposer, the two-dimensional pad architectures of microdevices were mapped to three-dimensional cylindrical layouts conforming to fibre geometry. Through connection with helical copper microwires, eight microdevices were thermally drawn into a machine-washable elastic fibre capable of more than 60% stretch. This programmable fibre, which incorporates a 32-bit floating-point microcontroller, independently performs edge computing tasks even when braided, woven, knitted or seam-sewn into garments. The universality of the assembly process allows for the integration of additional functions with simple modifications, including a rechargeable fibre power source that operates the computer for nearly 6 h. Finally, we surmount the perennial limitation of rigid interconnects by implementing two wireless communication schemes involving woven optical links and seam-inserted radio-frequency communications. To demonstrate its utility, we show that garments equipped with four fibre computers, one per limb, operating individually trained neural networks achieve, on average, 67% accuracy in classifying physical activity. However, when networked, inference accuracy increases to 95% using simple weighted voting.
