<p>Entanglement is a fundamental resource for various optical quantum information processing (QIP) applications. To achieve high-speed QIP systems, entanglement should be encoded in short wavepackets. Here we report the real-time observation of ultrafast optical Einstein–Podolsky–Rosen correlation at a picosecond timescale in a continuous-wave system. Optical phase-sensitive amplification using a 6-THz-bandwidth waveguide-based optical parametric amplifier enhances the effective efficiency of 70-GHz-bandwidth homodyne detectors, mainly used in 5G telecommunication, enabling its use in real-time quantum state measurement. Although power measurement using frequency scanning, such as an optical spectrum analyser, is not performed in real time, our observation is demonstrated through the real-time amplitude measurement and can be directly used in QIP applications. The observed Einstein–Podolsky–Rosen states show quantum correlation of 4.5 dB below the shot-noise level encoded in wavepackets with 40 ps period, equivalent to 25 GHz repetition—10³ times faster than previous entanglement observation in continuous-wave systems. The quantum correlation of 4.5 dB is already sufficient for several QIP applications, and our system can be readily extended to large-scale entanglement. Moreover, our scheme has high compatibility with optical communication technology such as wavelength-division multiplexing, and femtosecond-timescale observation is also feasible. Our demonstration is a paradigm shift in accelerating accessible quantum correlation—the foundational resource of all quantum applications—from the nanosecond to picosecond timescales, enabling ultrafast optical QIP.</p>