<p>Research on mental health has traditionally separated the study of ill-being, including clinically defined mental and behavioural disorders and subthreshold problems, from the study of well-being, which encompasses factors such as life satisfaction and positive affect. Although previous reviews of studies primarily using self-report scales indicate that ill-being and well-being are distinct yet interconnected constructs, a deeper examination of their relationship is lacking. In this Perspective, we synthesize genetic, biological, developmental, psychosocial, societal, cultural and clinical research on ill-being and well-being. Our review reveals substantial genetic overlap and similar biological underpinnings for ill-being and well-being. By contrast, environmental factors and societal changes often exert divergent influences. We propose a differentiated multidisciplinary framework in which the shared and unique determinants, predictors, mechanisms and consequences of mental ill-being and well-being vary across levels of analysis, offering a more nuanced understanding of the interconnections.</p>

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The nature of the relation between mental well-being and ill-being

  • Christian K. Tamnes,
  • Mona Bekkhus,
  • Maja Eilertsen,
  • Ragnhild B. Nes,
  • Monica Beer Prydz,
  • Eivind Ystrom,
  • Eira R. Aksnes,
  • Synøve N. Andersen,
  • Helga Ask,
  • Ziada Ayorech,
  • Tina Baier,
  • Dani Beck,
  • Eirik Jerven Berger,
  • Ludvig D. Bjørndal,
  • Olga D. Boer,
  • Marieke G. N. Bos,
  • Avshalom Caspi,
  • Rosa Cheesman,
  • Razieh Chegeni,
  • Laura Cortés-García,
  • Perline A. Demange,
  • Joakim C. Ebeltoft,
  • Maud Edvoll,
  • Nikolai Haahjem Eftedal,
  • Espen Moen Eilertsen,
  • Yuan Fang,
  • Lia Ferschmann,
  • Sam Fluit,
  • Siri H. Folstad,
  • Eivor Fredriksen,
  • Liridona Gashi,
  • Kristin Gustavson,
  • Thomas Hansen,
  • Live S. Hofgaard,
  • Valerie Karl,
  • Michal Kozák,
  • Kristian G. Krogshus,
  • Jinrui Liu,
  • Torkild H. Lyngstad,
  • Niamh MacSweeney,
  • Hermine H. M. Maes,
  • Lilian Mayerhofer,
  • Tom A. McAdams,
  • Terrie E. Moffitt,
  • Nasimeh Naseri,
  • Thomas S. Nilsen,
  • Linn B. Norbom,
  • Egil Nygaard,
  • Aurora Oftedal,
  • Willy Pedersen,
  • Qi Qin,
  • Rubén Rodríguez-Cano,
  • Vegard Skirbekk,
  • Dinka Smajlagic,
  • Ole Martin Solberg,
  • Anneli D. Tandberg,
  • Irene J. E. Teulings,
  • Fartein Ask Torvik,
  • Stella Tsotsi,
  • Vidar S. Ulset,
  • Emily G. Vira,
  • Espen Røysamb,
  • Tilmann von Soest

摘要

Research on mental health has traditionally separated the study of ill-being, including clinically defined mental and behavioural disorders and subthreshold problems, from the study of well-being, which encompasses factors such as life satisfaction and positive affect. Although previous reviews of studies primarily using self-report scales indicate that ill-being and well-being are distinct yet interconnected constructs, a deeper examination of their relationship is lacking. In this Perspective, we synthesize genetic, biological, developmental, psychosocial, societal, cultural and clinical research on ill-being and well-being. Our review reveals substantial genetic overlap and similar biological underpinnings for ill-being and well-being. By contrast, environmental factors and societal changes often exert divergent influences. We propose a differentiated multidisciplinary framework in which the shared and unique determinants, predictors, mechanisms and consequences of mental ill-being and well-being vary across levels of analysis, offering a more nuanced understanding of the interconnections.